ELLANN® Health – INUSpherese®. Ganzheitliche Entgiftung und Komplementärmedizin bei Umweltbelastungen, Autoimmunerkrankungen, Post-COVID und weiteren Erkrankungen. Häufig gestellte Fragen Generally diseases New Category New Category New Category Bei welchen Diagnosen kann die INUSpherese® helfen? ⎯⎯• Allergies ⎯⎯• Borreliose ⎯⎯• Chronical fatigue syndrome (CFS) ⎯⎯• Chronische Hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidämie ⎯⎯• Morbus Crohn ⎯⎯• Multiple Sklerose ⎯⎯• Multiples Chemikalien Hyper- sensitivitätssyndrom (MCS) ⎯⎯• Parkinson ⎯⎯• Long-COVID-Syndrome ⎯⎯• Post-Vac-Syndrom ⎯⎯• Rheuma (chronisch-entzündlich) ⎯⎯• Toxins ⎯⎯• and many more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for blood plasma purification and for supporting general well-being and health. Is INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpheresis® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal How much does an INUSpherese® treatment cost? Of course, we understand that the costs for comprehensive INUSpherese® therapy represent a significant investment. A complete treatment, which includes two sessions, a preparatory medical consultation and accompanying infusion concepts, usually costs between €5,400 and €5,700. This information is only intended to serve as a rough guide, as the exact costs can vary depending on your individual health condition and additional therapy options.To make it easier for you to access this innovative treatment, we offer interest-free installment payments of up to six months upon consultation. The amount of the installments can be freely determined. Please do not hesitate to contact us about this possibility; the financial hurdle should not be an obstacle to your health and well-being. As part of your therapy planning, you will receive detailed advice and a cost overview tailored to your individual health goals. PART OF ELLANN® INUSpherese® Center Berlin, blood wash, apheresis, consultation room ELLANN® INUSpherese® Center Berlin, blood wash, apheresis ELLANN Health ELLANN INUSpheresis Center Berlin, blood wash, apheresis ELLANN Health consultation room ELLANN INUSpheresis Center Berlin, blood wash, apheresis, consultation room VIP Room - ELLANN INUSpheresis Center Berlin ELLANN INUSpheresis Center Berlin, blood wash, apheresis, VIP treatment room ELLANN® INUSpherese® Center Berlin, blood wash, apheresis, consultation room ELLANN® INUSpherese® Center Berlin, blood wash, apheresis ELLANN Health ELLANN INUSpheresis Center Berlin, blood wash, apheresis ELLANN Health consultation room ELLANN INUSpheresis Center Berlin, blood wash, apheresis, consultation room VIP Room - ELLANN INUSpheresis Center Berlin ELLANN INUSpheresis Center Berlin, blood wash, apheresis, VIP treatment room ELLANN® INUSpherese® Center Berlin, blood wash, apheresis, consultation room ELLANN® INUSpherese® Center Berlin, blood wash, apheresis ELLANN Health ELLANN INUSpheresis Center Berlin, blood wash, apheresis ELLANN Health consultation room ELLANN INUSpheresis Center Berlin, blood wash, apheresis, consultation room VIP Room - ELLANN INUSpheresis Center Berlin ELLANN INUSpheresis Center Berlin, blood wash, apheresis, VIP treatment room Beratungstermin INUSpheresis® INUSpheresis® for Long COVID Autoimmune Disease Detoxification Chronic Inflammation Metabolic Diseases INUSpheresis® Studies Diseases Treatments ELANN® AI SEARCH ELLANN® since September 1, 2023 in the heart of Berlin We from ELLER KELLERMANN® have opened ELLANN®, the first INUSpherese® center in the heart of the vibrant city of Berlin. We have expanded our range of specialized detoxification procedures and therapies in the area of plasma apheresis in order to meet the continually growing demand. In our tastefully designed rooms, we not only offer innovative therapies, but also a welcoming atmosphere with a breathtaking panoramic view of Potsdamer Platz. Here you can feel completely comfortable. Enjoy the combination of state-of-the-art procedures and an inspiring environment and arrange a consultation appointment. Consultation appointment Get individual advice Just let us know your concerns and we will get back to you soon by phone or email. Vorname Nachname Email Telefonnummer Nachricht Before you make an appointment for a consultation with us, we ask you to familiarize yourself with the general patient information. These are available here and in our media library. Patient information Ihre Beratungsanfrage ist erfolgreich gesendet. Wir werden uns umgehend bei Ihnen melden. Beratungsanfrage senden Doctolib Dr. med. univ. Birgit Bernadette Heinisch-Röchert Medical Director – ELLANN® Our focus at ELLANN® is on holistic detoxification and evidence-based complementary medicine. The INUSpheresis® we use is a treatment method that helps the body eliminate harmful proteins (such as malformed antibodies), metabolic products (such as cholesterol) and toxic substances (such as heavy metals and microplastics). Our goal is to bring the disturbed metabolism, the inflammatory processes and the immune system back into natural balance. We use INUSpheresis® in various areas of application, including environmental stress, rheumatic diseases, lipid diseases, chronic inflammation as well as after infectious diseases and autoimmune diseases. For more information, see Frequently Asked Questions. Discover our unique treatment concept for holistic health. From diagnosis and treatment to aftercare and prevention – with us you are in the best hands. Medical Director Dr. med. univ. Birgit Bernadette Heinisch-Röchert The INUSpheresis® healing process Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn’s disease ⎯⎯• Multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson’s ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpheresis®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a dialysis of blood? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpheresis® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpheresis® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced at €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked questions Videos PFAS / Toxic chemical in Germany _ ARD reporting Link to video Bloodcleanse after chemotherapy _ Bild reporting Link to video 'Detox for the blood". _ Elle article Link to video

In Deutschland leidet etwa jeder dritte Mensch an Schilddrüsenproblemen, wobei ein Mangel an Schilddrüsenhormonen (Unterfunktion) häufig vorkommt. Etwa drei Prozent der Bevölkerung entwickeln eine chronische Entzündung namens Hashimoto-Thyreoiditis (auch kurz Hashimoto genannt). HASHIMOTO THYREOIDITIS Homepage / Diseases / Autoimmune Diseases / Hashimoto's Thyroiditis In Germany, around one in three people suffers from thyroid problems, with a lack of thyroid hormones (underactive function) being common. About three percent of the population develops a chronic inflammatory condition called Hashimoto's thyroiditis (also known as Hashimoto's for short). This autoimmune disease causes the body's immune system to mistakenly attack the cells of the thyroid gland. This disease usually occurs between the ages of 30 and 50, with women being affected more often. The signs are often initially misinterpreted as menopausal symptoms. There are two forms of Hashimoto's thyroiditis: Atrophic form The thyroid tissue is gradually destroyed and the thyroid shrinks. This form is the most common. Hypertrophic form In the rarer form, the thyroid gland enlarges and a palpable goiter (goiter) forms. Hashimoto's Thyroiditis Causes of Hashimoto Thyroiditis Causes of Hashimoto Thyroiditis The exact triggers for Hashimoto's are still being fully researched. It is discussed that family predisposition, hormonal changes (such as birth or menopause), psychological stress, severe viral infections (such as Pfeiffer's glandular fever, shingles) and hormonal problems of the adrenal cortex can be possible triggers. Environmental influences Environmental influences are also discussed, such as exposure to heavy metals, pesticides and numerous other everyday toxins. But smoking, stress, infections (especially hepatitis type C), an excess of iodine and a deficiency of selenium or vitamin D are also discussed as triggers for inflammation of the thyroid. Symptoms of Hashimoto's Thyroiditis Hashimoto's does not usually cause pain and therefore often goes unnoticed. Initially, temporarily high levels of thyroid hormones may occur, causing signs of hyperthyroidism such as weight loss, nervousness, and heart palpitations. As the inflammation progresses and further damages the thyroid tissue, it leads to an underactive thyroid. The slowing of metabolic processes can lead to the following symptoms: ⎯⎯• Exhaustion and tiredness ⎯⎯• Dejection and depressive mood ⎯⎯• Memory problems and difficulty concentrating ⎯⎯• Freezing and sensitivity to cold ⎯⎯• Constipation and bloated stomach ⎯⎯• Weight gain despite a normal diet ⎯⎯• Dry skin, brittle hair and hair loss ⎯⎯• Susceptibility to infections ⎯⎯• Compulsion to clear the throat and cough, voice changes ⎯⎯• Menstrual cycle disorder in women ⎯⎯• Potency disorders in men ⎯⎯• Cardiac arrhythmia, slow heartbeat ⎯⎯• Water retention ⎯⎯• Hearing loss ⎯⎯• Muscle pain Depending on the course and severity, different symptoms can occur in each patient and not all symptoms always occur. Treatment options for Hashimoto's thyroiditis Hashimoto's thyroiditis is not curable. It is treated with hormone tablets that compensate for the lack of thyroid hormones. Treatment is usually aimed at relieving symptoms, balancing hormone levels by administering hormones and slowing the progression of the disease. However, this does not cure the autoimmune disease. Other influencing factors such as diet, stress, environmental influences and even the quality of sleep have a significant influence on the long-term success of the therapy, the improvement of symptoms and the effective prevention of new attacks in Hashimoto. Because the immune system is overactive in Hashimoto's, it is crucial to minimize potential triggers for this overreaction as much as possible. INUSpheresis® INUSpheresis® as an accompanying therapy for Hashimoto In the case of Hashimoto's, the first priority is to get the antibodies' attacks on the thyroid under control and thus bring the inflammation levels to the lowest possible range. Therefore, at ELLANN® we use INUSpheresis® as a useful complementary therapy option to specifically remove heavy metals and other environmental toxins as well as inflammatory proteins. Autoimmune diseases INUSpheresis Details There have already been various studies on the effectiveness of theINUSpheresis ® carried out. These show promising results in the treatment of various diseases such asUlcerative colitis ,rheumatoid arthritis ,Polyneuropathy ,Crohn's disease . We have put together some interesting studies for you here. Study situation News & study situation Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Datenschutz I DSVGO. Informationen über die Erhebung personenbezogener Daten auf unserer Homepage ​ Sehr geehrte Besucherin, sehr geehrter Besucher unserer Homepage, wir möchten Sie darüber informieren, dass beim Besuch unserer Homepage personenbezogene Daten erhoben werden. Personenbezogen sind Daten, die auf Sie persönlich beziehbar sind (z. B. Name, E-Mail, Nutzerverhalten). PART OF Homepage / Data Protection Data Protection Information about the collection of personal data on our homepage Dear visitor to our homepage, we would like to inform you that personal data is collected when you visit our homepage. Personal data is data that can be related to you personally (e.g. name, email, user behavior). Responsible for collecting and storing data in our practice is: c/o INUSpheresis Center Berlin GbR Leipziger Platz 15 10117 Berlin Germany Your rights regarding the data we hold about you You have the following rights towards us: Right to rectification and deletion Right to data portability Right to restriction of processing Right to information Right to object to processing You will receive free information at any time about the personal data we have stored about you as well as the origin, recipient and purpose of data collection and data processing. You also have the right to request that your data be corrected, blocked or deleted. Excluded from this are data that must be stored due to legal regulations, such as in the context of our statutory health insurance activities within the framework of SGB V. So that a data block can be implemented at any time, data is kept in an internal block file for control purposes. If data is not collected by a legal archiving requirement, we will delete your data at your request. If the archiving requirement applies, we will block your data. For all questions and concerns regarding the correction, blocking or deletion of personal data, please contact the contact persons listed above using the contact details in this data protection declaration. You also have the right to complain to a data protection supervisory authority about our processing of your personal data. The responsible supervisory authority for the state of Berlin: Berlin Commissioner for Data Protection and Freedom of Information, Friedrichstraße 219, 10969 Berlin Collection of personal data when you visit our website: Our homepage serves exclusively to provide information about our practice, our range of treatments and therapeutic and diagnostic options for various diseases. When you visit our homepage, only the data that is transmitted from your browser to our server is collected. This data is necessary so that you can see our homepage and navigate it. The legal basis for collecting the data is Article 6 Paragraph 1 f) of the EU General Data Protection Regulation. Specifically, the following data is collected when you visit our homepage: IP address Type of browser, as well as its language and version Operating system and its interface Access status/http status code Date and time of the request, as well as the time zone Content of the request and homepage from which it comes Amount of data transferred This data will be deleted when it is no longer required. Cookies: In addition to this data, we also use cookies on our homepage. These are small text files that are saved on your computer (in your browser) after you visit our homepage. If you then visit our homepage again, the browser you are using will send the information stored in the cookie to our homepage and can, for example, make navigation easier because default settings are adopted. Cookies are not viruses and cannot install malware or spy programs on the computer. They are short texts that are exchanged between the web server and browser. The following types of cookies are used on our homepage: Transient cookies (temporary cookies) These cookies are only stored for the duration of your browser use. These store a so-called session ID, with which various requests from your browser can be assigned to the shared session. This allows your computer to be recognized when you return to the homepage. As soon as you close the browser, these cookies are automatically deleted. Persistent cookies (time-limited cookies) These cookies only differ from transient cookies in that they are not automatically deleted when the browser is closed, but only after a preset time. However, you can delete these cookies at any time via your browser settings. You can also use our homepage without the use of cookies, which may mean that some of the displays and functions of our offering may only work to a limited extent. If you would like to deactivate cookies, you can do this via special settings in your browser. The best way to do this is to use your browser's help function to make the appropriate changes. You can generally display and manage online advertising cookies via the following links: Contact form / email contact: If you send us appointment requests or inquiries via email or contact form on our homepage, the data you provide (email address, name, telephone number) will be stored in order to be able to answer your questions. This data will be deleted as soon as it is no longer needed and there are no legal retention requirements. This data will not be made accessible to third parties. Please note that we will receive your data from the contact form via email in the practice. The transmission is encrypted. IT experts often remind people of the principle that if you wouldn't send it as a postcard, you shouldn't send it by email. Therefore, please do not send us any confidential information/data by email or using the contact form on the homepage, but rather by post or telephone. Please understand that we decline any liability for unsolicited data/e-mails. Collection of access data / server log files: The delivery and presentation of content via our homepage technically requires the collection of certain data. When you access our homepage, these so-called server log files are recorded by us or the web space provider. The corresponding information consists of the name of the homepage, the file, the current date, the amount of data, the web browser and its version, the operating system used, the domain name of your Internet provider, the referrer URL as the page from which you have switched to our site, as well as the corresponding IP address. These log files do not allow any conclusions to be drawn about you or yourself. We use this data to display and deliver our content and for statistical purposes. The information supports the provision and constant improvement of our offering. We also reserve the right to subsequently check the data mentioned if there is suspicion of illegal use of our offer. Objection to advertising emails: As part of the legal imprint obligation, we have to publish our contact details. These are sometimes used by third parties to send unwanted advertising and information. We hereby object to any sending of advertising material of any kind that we have not expressly authorized. We also expressly reserve the right to take legal action against the unwanted and unsolicited sending of advertising material. This applies in particular to so-called spam emails, spam letters and spam faxes. We would like to point out that the unauthorized transmission of advertising material can affect competition law, civil law and criminal law. Spam emails and spam faxes in particular can result in high costs. Claims for damages on our part may result if they disrupt practice operations by overfilling mailboxes or fax machines. Third Party Content and Services: The offer on our homepage may also include content, services and services from other providers that complement our offer. On the one hand, this happens with so-called plug-ins. These are software extensions or additional modules that expand the functions of our homepage. Examples of such offers are maps from Google Maps, YouTube videos or graphic representations from third parties. Accessing these services from third parties regularly requires the transmission of your IP address. This makes it possible for these providers to perceive your user IP address and also store it. We make every effort to only include third parties that use IP addresses solely to deliver the content. However, we have no influence on which third party may store the IP address. This storage can, for example, serve statistical purposes. If we become aware of storage processes by third parties, we will immediately inform our users of this fact in this data protection declaration. In this context, please also note the following special data protection declarations for individual third-party providers and service providers whose services we use on our homepage. You can also find these in this data protection declaration. Google Analytics: We use Google Analytics on our homepage. Google Analytics is a web analysis service provided by Google Inc. Google uses cookies. The information generated by cookies about the use of the homepage is usually transferred to a Google server in the USA and stored there. Google uses this information on our behalf to evaluate the use of our online offering and to provide us with other services related to the use of this online offering and internet usage. We have expanded Google Analytics to include the code “anonymizeIP”. This means that the IP address of users is shortened by Google within member states of the European Union or in other contracting states to the Agreement on the European Economic Area. In exceptional cases, the full IP address is transmitted to a Google server in the USA and shortened there. The code extension “anonymizeIp” caps the last 8 bits of the user’s IP address. By using this code, only a rough localization of users is possible. The IP address transmitted by the user's browser is not merged with other Google data. You can prevent the storage of cookies by setting your browser software accordingly. It may then not be possible to use all functions of the homepage to their full extent. You can also prevent Google from collecting the data generated by the cookie and relating to your use of the online offering and from processing this data by Google by downloading and installing the browser plug-in available under the following link: http://tools.google.com/dlpage/gaoptout?hl=de . It is also possible to set an opt-out cookie, which prevents the future collection of your data when you visit our homepage. Information on integrating an opt-out cookie can be found at: http://developers.google.com/analytics/devguides/collection/gajs/?hl=de#disable . Further information on data use by Google, settings and objection options can be found on the Google websites (“Use of data by Google when you use our partners’ homepages or apps”): https://www.google.com/intl/de/policies/privacy/partners/ . Google's privacy policy and terms of use can be found at: http://www.google.com/policies/technologies/ads (“Advertising”). 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The content of the plug-in is transmitted directly to your browser by Facebook and integrated into the homepage. By integrating the plug-ins, Facebook receives the information that you have accessed the corresponding page on our homepage. If you are logged in to Facebook, Facebook can assign the visit to your Facebook account. Please note that this information is exchanged when you visit our homepage, regardless of whether you interact with the plug-ins. If you interact with the plug-ins, for example by clicking the “Like” button, the corresponding information is transmitted from your browser directly to Facebook and stored there. For Facebook, your visit to our site is assigned to your user account. We have no knowledge of what type of content is transmitted to Facebook or how Facebook uses it. The purpose and scope of data collection and the further processing and use of the data by Facebook as well as your related rights and setting options to protect your privacy can be found in Facebook's data protection information ( http://www.facebook.com/policy.php ). Google+ plug-in (Google Plus plug-in): We use Google+ functions on our homepage. The social network is operated by Google Inc., 1600 Amphitheater Parkway, Mountain View, CA 94043, USA. Google+ allows you to publish content globally through its button. You will also be offered personalized content from Google and partner providers. Google saves your rating (+1) on the content and information of homepages that you clicked on when you assigned a +1. Your +1 rating can be displayed with your profile name and photo in other Google services. Google tracks your overall 1+ activities. This collection serves to optimize and personalize the Google offer for you. 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Das Alzheimer-Demenz-Syndrom, umgangssprachlich kurz Alzheimer genannt, ist eine Art Demenz, die für gewöhnlich Personen ab 65 Jahren betrifft. Das langsam fortschreitende Absterben von Nervenzellen im Gehirn durch Proteinablagerungen führt zu Gedächtnisverlust, Verwirrtheit und Desorientierung.  ALZHEIMER DEMENTIA SYNDROME Homepage / Diseases / Chronical Inflammation / Alzheimer Dementia Syndrome Alzheimer's dementia syndrome, colloquially known as Alzheimer's for short, is a type of dementia that usually affects people aged 65 and over. The slowly progressive death of nerve cells in the brain due to protein deposits leads to memory loss, confusion and disorientation. Alzheimer Dementia Syndrome Causes of Alzheimer dementia syndrome Causes The exact causes of accelerated brain deterioration in Alzheimer's dementia are not yet fully understood. Both genetic and environmental factors are thought to play a role. A family predisposition can increase the risk of Alzheimer's disease. Age and hereditary factors are believed to have a major influence on the likelihood of developing Alzheimer's dementia. Deposition of plaques in the brain Protein deposits in the brain play an important role in the development of Alzheimer's dementia. Two types of proteins have been identified, called beta-amyloid and tau. In Alzheimer's patients, these proteins are deposited in the brain in the form of plaques and fibrils. Normally these proteins are broken down. In Alzheimer's patients, this clean-up process in the brain no longer works, which inhibits the energy and oxygen supply to the brain and the nerve cells ultimately die. Genetic predisposition 5-15% of people who develop Alzheimer's disease have a familial history. In half of these cases, Alzheimer's occurs early, before the age of 65, and is usually caused by certain changes in the genetic makeup, more specifically in the gene called ApoE (Apo-Lipoprotein E). Risk factors that promote the disease ⎯⎯• High blood pressure ⎯⎯• Diabetes ⎯⎯• Lipid metabolism disorders ⎯⎯• Excessive alcohol consumption Other factors that can increase the risk of Alzheimer's dementia include advanced age, female gender and certain lifestyle factors such as unhealthy diet, lack of exercise and social isolation. Environmental influences Environmental influences are often discussed as potential causes of Alzheimer's. There are some environmental factors that are associated with an increased risk of developing Alzheimer's: ⎯⎯• Air pollution Studies suggest that long-term exposure to air pollution, particularly particulate matter, may increase the risk of Alzheimer's disease. ⎯⎯•Harmful chemicals Exposure to certain harmful chemicals, such as lead and mercury, has also been linked to an increased risk of Alzheimer's disease. ⎯⎯•Pesticides and herbicides Some research suggests that exposure to pesticides and herbicides may increase the risk of Alzheimer's disease. However, it is important to note that Alzheimer's is a complex disease with many factors at play. Environmental influences alone cannot reliably explain the development of Alzheimer's disease. Research in this area is still ongoing, and further studies are needed to understand the precise links between environmental factors and Alzheimer's disease. Symptoms of Alzheimer's dementia syndrome Symptoms of Alzheimer's disease usually develop gradually and worsen over time. The main difference from other dementias is that Alzheimer's usually affects short-term memory rather than other mental abilities. This manifests itself, for example, in repetitive questions, frequently misplacing objects, forgetting appointments or assigning names to familiar faces. Alzheimer's disease is otherwise associated with many similar symptoms to other dementias, such as: ⎯⎯• Memory loss ⎯⎯• Problems with language ⎯⎯• Personality changes ⎯⎯• Disorientation ⎯⎯• Problems coping with tasks in daily life ⎯⎯• fears ⎯⎯• depressions ⎯⎯• sleep disorders ⎯⎯• Illusions ⎯⎯• Aggressive or inappropriate behavior Not every person with Alzheimer's has all of these symptoms. The course of the disease can vary from person to person. Treatment options for Alzheimer's dementia syndrome Treatment primarily focuses on relieving symptoms and improving patients' quality of life. There is currently no cure for Alzheimer's dementia. Treatment usually includes a combination of drug and non-drug therapy. Medication ⎯⎯• Cholinesterase inhibitors are often prescribed to relieve cognitive symptoms ⎯⎯• Memantine can be used in combination with Cholinesterase inhibitors may be prescribed to relieve neurological symptoms ⎯⎯• Anti-dementia medications can be used to improve memory and slow disease progression Non-drug therapy ⎯⎯• Occupational therapy ⎯⎯• Music therapy ⎯⎯• Physiotherapy ⎯⎯• Social activities ⎯⎯• Memory training Diet and lifestyle A balanced diet, regular physical activity and mental stimulation can help slow the progression of the disease. In addition, the support of relatives plays an important role in the treatment of Alzheimer's dementia. Building a safe and supportive environment, providing information and training, and social inclusion can help improve patient well-being. It is important to note that Alzheimer's dementia is a progressive disease and that treatment is aimed at relieving symptoms and slowing the progression of the disease rather than curing it. INUSpheresis® INUSpherese® for Alzheimer's dementia syndrome INUSpheresis® is a therapeutic method used in the treatment of Alzheimer's and other neurological diseases. It is a form of blood plasma purification that aims to rid the body of harmful substances such as toxins, inflammatory mediators and pathogenic proteins. For many neurodegenerative diseases, such as Alzheimer's or Parkinson's, brain detoxification is indicated as part of the treatment. In addition to the protein accumulations already mentioned, it is often the light and heavy metal contamination that has accumulated in the brain and can no longer be effectively detoxified. This is where INUSpheresis® comes into play. It is a special form of blood washing that aims to specifically rid the body of harmful substances such as toxins, heavy and light metal contamination, fat accumulation in the blood, inflammatory mediators and pathogenic proteins. INUSpheresis® aims to reduce existing inflammation and support the brain in detoxification. However, it is important to emphasize that INUSpherese® therapy is not a cure for Alzheimer's, but can lead to an improvement in the symptoms and progression of the disease. Treatment results may vary depending on individual cases. We will use INUSpheresis® for various chronic diseases, including autoimmune diseases, chronic inflammation, environmental stresses and other health problems such as long-COVID. Treatment INUSpheresis Details Current therapeutic approaches to treating Alzheimer's disease remain disappointing, leaving an urgent need for effective treatments. In this study, we provide an overview of the emerging role of "metabolic inflammation" and stress as a key factor in the pathogenesis of Alzheimer's disease and propose a new concept to correct metabolic inflammation, increase resistance, and potentially slow or stop it Stopping the progression of the neurodegenerative process. Based on recent findings and the observations of an initial pilot test in 2020, we assume that extracorporeal apheresis can be used to treat Alzheimer's disease. Apolipoprotein E, lipoprotein(a), oxidized LDL (low density lipoprotein) and large LDL particles, as well as other pro-inflammatory lipids and stress hormones such as cortisol, are known to be key factors in the formation of amyloid plaques and the exacerbation of Alzheimer's disease. After extracorporeal double-membrane apheresis in patients with Alzheimer's disease, there was a significant reduction in proinflammatory lipids, circulating cytokines, immune complexes, proinflammatory metals, and toxic chaperones. Study Situation Studies & Publications Alzheimer's study Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Die Multiple Sklerose ist eine autoimmune, chronisch-entzündliche Erkrankung des zentralen Nervensystems. Bei der MS greift das Immunsystem fälschlicherweise die Nerven im Gehirn und Rückenmark an und schädigt diese. Das Wort Sklerose bedeutet Narbenbildung. Es entstehen „Narben auf Nerven“, wodurch diese nicht mehr richtig arbeiten können. MULTIPLE SCLEROSIS Home page /diseases /Autoimmune diseases / Multiple Sk Multiple sclerosis is an autoimmune, chronic inflammatory disease of the central nervous system. In MS, the immune system mistakenly attacks and damages the nerves in the brain and spinal cord. The word sclerosis means scarring. “Scars appear on nerves,” meaning they can no longer work properly. MS mostly occurs in young people (between the ages of 20 and 40), and is twice as common in women as in men. Multiple Sclerosis (MS) causes The exact mechanism of how chronic fatigue syndrome develops has so far only been partially understood. The disease begins with an infection - usually in full health. Possible triggers can be: ⎯⎯• Epstein-Barr virus (EBV) and other herpes viruses ⎯⎯• Dengue viruses ⎯⎯• Coxsackie viruses ⎯⎯• Influenza ⎯⎯• Borrelia ⎯⎯• Bacteria (Legionella, Coxial) There are a number of proven connections that suggest that CFS is an autoimmune disease in at least some patients. Most people with chronic fatigue syndrome are highly productive until the disease occurs. As a rule, the disorder occurs suddenly and often after a stressful event. These risk factors include: ⎯⎯• Immune defects ⎯⎯• Other cases in the family ⎯⎯• Vulnerable phase with physical or psychological stress Causes of MS Causes of MS The cause of MS is still unknown. However, most doctors believe those affected may have been exposed to a virus or unknown substance at a young age. This exposure may have caused the immune system to attack the body's own tissue, triggering an autoimmune reaction. However, the exact connection is not yet known. It is further believed that a combination of genetic, environmental and immunological factors contribute to this condition. There are some theories that point to specific causes: Genetic predisposition There is evidence that MS has a genetic component. People with a family member who has MS are at higher risk of developing the disease themselves. Environmental influences Certain environmental and geographical conditions can also influence the risk of MS. The closer a person grows up to the equator, the lower their risk of MS. The risk increases further south and north. Northern Europe and North America have the highest incidence rates. A vitamin D deficiency due to too little sunlight may play a role. In addition, among other things, Viral infections (e.g. caused by measles viruses, herpes viruses or Epstein-Barr viruses), Lyme disease and smoking are discussed. It is important to note that autoimmune diseases can vary widely and not all of these factors play a role in every case. The exact cause can vary from disease to disease. Environmental factors as triggers Chronic inflammation has been increasing worldwide for decades, and the causes are diverse. Environmental toxins, which are ubiquitous, especially in industrialized countries, play an important role. New chemicals that are not beneficial to human health have found their way into our daily lifestyle. They can be found in household cleaning products, personal care products, cosmetics, textiles, indoor pollution, air pollution and, above all, in food. Depending on the individual's ability to detoxify, these chemicals accumulate in different tissues and organs. This can lead to numerous health problems, including eye disease, heart problems, kidney and thyroid disease, and neurological disorders. Clinical pictures and effects Primär-chronische Entzündungen Sekundär-chronische Entzündungen Primary chronic inflammation develop gradually and manifest themselves through slow or intermittent symptoms. The duration of an inflammatory attack often lasts longer than four weeks and complete healing is usually not possible. Examples of primary chronic inflammation are diseases such as type 1 diabetes or autoimmune diseases such as rheumatoid arthritis, multiple sclerosis or Crohn's disease, in which the symptoms gradually progress. Learn more Secondary chronic inflammationusually occur after an acute inflammation that has not completely healed. The healing process is often lengthy. Examples of such chronic forms are diseases such as chronic hepatitis, chronic myocarditis, stomach ulcer (ulcer) or chronic tonsillitis. These often occur after untreated acute inflammation and manifest as long-lasting problems. Learn more A variety of diseases can be caused by chronic inflammation. We differentiate between primary-chronic inflammation and secondary-chronic inflammation: Symptoms of MS Because MS attacks different nerves, patients' symptoms vary. The pattern in which symptoms appear and subside also varies. Early symptoms and signs of illness that occur particularly frequently in MS are: ⎯⎯• Spastic paralysis symptoms ⎯⎯• Visual problems with blurred or foggy vision as an expression of inflammation of the optic nerves (optic neuritis) ⎯⎯• Sensation disorders of the skin (“sensitivity disorders”), usually in the form of tingling, (painful) sensations or a feeling of numbness ⎯⎯• Uncertainty when walking or grasping ⎯⎯• Double vision ⎯⎯• Bladder disorders ⎯⎯• “Slurred” speech Multiple sclerosis can also cause numerous other symptoms, which can occur individually or in combination. These later symptoms of MS are: ⎯⎯• Spastic paralysis symptoms ⎯⎯• Problems controlling the urge to urinate or defecate ⎯⎯• Difficulty with balance and walking ⎯⎯• Fatigue and feeling weak ⎯⎯• Slow, slurred speech ⎯⎯• Depressive moods and depression ⎯⎯• Limitations in attention, memory and concentration. ⎯⎯• Pain ⎯⎯• Dizziness ⎯⎯• Sexual dysfunctions Pains swelling Inflammation often leads to swelling and can cause tissue damage. Redness Inflamed areas may be red and warmer than the surrounding skin. Stiffness Joints can become stiff and less mobile when affected by inflammation. exhaustion Chronic inflammation can cause general tiredness and fatigue. Fever An increased body temperature can indicate inflammation, although this is not always the case. weight loss For some people, chronic inflammation can lead to unwanted weight loss. Organ change Depending on the area affected, chronic inflammation can lead to permanent organ damage. anamnese The detailed medical history survey serves to collect information about symptoms, previous history and possible risk factors. Physical examination A thorough physical examination may reveal evidence of inflammation, such as swelling, redness, pain, or limited mobility. Laboratory tests In laboratory tests, doctors use special blood tests to determine whether there is inflammation in the body. Various markers are examined here: C-reactive protein (CRP): This is where the biomarker CRP is determined in the blood, which is often used to assess inflammation in the body. Erythrocyte sedimentation rate (ESR): The ESR measures how quickly red blood cells settle in the blood. This value is often used to detect inflammation or other diseases in the body. Interleukins 1, 6 and 8: The values provide information about the presence of inflammatory messengers called interleukins, which are crucial in the body's immune response to infections and inflammation. Tumor necrosis factor alpha (TNF-α): This test examines TNF-α in the blood, a protein that is involved in inflammatory processes. Imaging procedures Depending on whether a particular inflammation is suspected, an imaging test such as X-rays, CT scans or MRI scans may be required to examine the affected areas in more detail. biopsy In some cases, a tissue biopsy may be necessary to make an accurate diagnosis. This involves taking a small sample of tissue and examining it under a microscope. Endoscopy If there is inflammation in the digestive tract, an endoscopy can be performed to more accurately assess the condition of the mucous membrane. Diagnostics for chronic diseases Chronic inflammatory diseases often affect more than just one organ system. The diagnosis of chronic inflammation can be complex and depends on the type of inflammation and the patient's individual circumstances. At ELLANN® we work together with specialized doctors on an interdisciplinary basis, because thorough diagnostics are essential for optimal therapy planning. Below are some common diagnostic procedures for chronic inflammation: Diagnostics for chronic diseases Chronic inflammatory diseases often affect more than just one organ system. The diagnosis of chronic inflammation can be complex and depends on the type of inflammation and the patient's individual circumstances. At ELLANN® we work together with specialized doctors on an interdisciplinary basis, because thorough diagnostics are essential for optimal therapy planning. Below are some common diagnostic procedures for chronic inflammation: anamnese The detailed medical history survey serves to collect information about symptoms, previous history and possible risk factors. Physical examination A thorough physical examination may reveal evidence of inflammation, such as swelling, redness, pain, or limited mobility. Laboratory tests In laboratory tests, doctors use special blood tests to determine whether there is inflammation in the body. Various markers are examined here: C-reactive protein (CRP): This is where the biomarker CRP is determined in the blood, which is often used to assess inflammation in the body. Erythrocyte sedimentation rate (ESR): The ESR measures how quickly red blood cells settle in the blood. This value is often used to detect inflammation or other diseases in the body. Interleukins 1, 6 and 8: The values provide information about the presence of inflammatory messengers called interleukins, which are crucial in the body's immune response to infections and inflammation. Tumor necrosis factor alpha (TNF-α): This test examines TNF-α in the blood, a protein that is involved in inflammatory processes. Imaging procedures Depending on whether a particular inflammation is suspected, an imaging test such as X-rays, CT scans or MRI scans may be required to examine the affected areas in more detail. biopsy In some cases, a tissue biopsy may be necessary to make an accurate diagnosis. This involves taking a small sample of tissue and examining it under a microscope. Endoscopy If there is inflammation in the digestive tract, an endoscopy can be performed to more accurately assess the condition of the mucous membrane. Treatment options for MS There are various treatment options for MS, which can vary depending on the course of the disease, severity and individual needs. Drug therapies There are several medications used to treat MS, aimed at modifying the course of the disease, reducing inflammation, and relieving symptoms. These include immunomodulators, immunosuppressants, steroids and newer medications such as monoclonal antibodies. Physiotherapy and rehabilitation These therapies can help improve physical functionality, manage symptoms, and increase quality of life. This includes physical therapy, occupational therapy, speech therapy and other rehabilitation measures. Supportive therapies This includes symptom relief measures such as pain management, nutritional advice, psychological support and counseling. Lifestyle adjustments A healthy lifestyle with a balanced diet, regular exercise and stress management can have a positive influence on the course of the disease. It is important that the treatment of MS is individualized and carried out in consultation with a doctor or neurologist. New treatment options and research results can further develop therapy options, so it is advisable to regularly keep yourself informed about current developments. INUSpheresis® INUSpherese® as an accompanying therapy option for MS There is currently no cure for multiple sclerosis, only options to alleviate the symptoms. If symptoms worsen acutely during standard drug therapy, more intensive treatment and the use of additional procedures may be helpful. INUSpherese® therapy shows promising results in some MS patients by effectively filtering known factors such as heavy metals and other environmental toxins, inflammatory mediators, autoimmune antibodies, pro-inflammatory cytokines and immune complexes from the blood. This treatment aims to reduce harmful substances, improve blood flow in small blood vessels and ensure that the body receives sufficient oxygen. This is intended to slow down damage that leads to deterioration in the course of the disease. Our medical team at ELLANN® advises patients with MS and their relatives individually on the available treatment options and provides information on whether INUSpheresis® is indicated as an accompanying therapy procedure to alleviate symptoms. Please arrange a consultation appointment. doctors INUSpheresis Details Various studies have already been carried out on the effectiveness of INUSpherese®. These show promising results in the treatment of various diseases such asUlcerative colitis ,rheumatoid arthritis ,Polyneuropathy ,Crohn's disease . We have put together some interesting studies for you here. Study situation News & study situation Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Morbus Crohn ist, wie auch die Colitis ulcerosa, eine chronisch-entzündliche Darmerkrankung. Es handelt sich um eine komplexe Barriere-Erkrankung, bei der die Schutzfunktion der Darmschleimhaut, die normalerweise als Barriere gegen Bakterien und Fremdstoffe wirkt, gestört ist. CROHN'S DISEASE Homepage / Diseases / Chronic inflammation / Morbus Crohn Morbus Crohn, like ulcerative colitis, is a chronic inflammatory bowel disease. It is a complex barrier disease in which the protective function of the intestinal mucosa, which normally acts as a barrier against bacteria and foreign substances, is disrupted. This disorder, combined with the reduced ability of certain cells to recognize and fight bacteria, allows bacteria to invade the intestines, which in turn results in an immune reaction and the inflammation that is triggered. This long-term inflammation ultimately leads to tissue damage. In contrast to ulcerative colitis, Crohn's disease can manifest itself in the entire digestive tract from the oral cavity to the anus, often affecting the lower section of the small intestine or large intestine. Another important feature of Crohn's disease is that, unlike ulcerative colitis, the inflammation affects all layers of the wall. As a result, the inflammation can spread more quickly into adjacent tissue structures and organs (such as the urinary bladder, ovaries and uterus) and cause abscesses or fistulas, which make therapy more difficult and further limit the quality of life of those affected. Morbus Crohn Causes of Morbus Crohn's disease Causes of Morbus Crohn's disease In the past, Morbus Crohn's disease was classified as a classic autoimmune disease, but we now know that it is actually an immune-associated disease. This means that the immune response that contributes to inflammation is not innate to the body, as is the case with autoimmune diseases. The exact causes of Crohn's disease are still not fully understood. However, chronic inflammatory bowel diseases always have complex backgrounds. Genetic predisposition In some cases of the disease there is a hereditary component. Mutations in certain genes that affect immune system function, intestinal barrier function, or inflammatory response may increase susceptibility to Crohn's disease. For example, changes in genes such as NOD2 and ATG16L1 have been linked to an increased risk of Crohn's disease. About half of patients with Crohn's disease have changes in the NOD2 gene. The level of risk depends on how severe the changes are and whether both genes are affected. immune system It is assumed that there is a disorder in the interaction between the intestinal immune system and the bacterial intestinal flora. Common intestinal bacteria invade the lining of the intestine, triggering an excessive immune response. Immune cells penetrate the tissue and continuously release inflammatory messenger substances. The immune system can also attack healthy tissue. In addition to the typical signs of inflammation, cell death and changes in tissue lead to progressive damage to the intestines. Numerous inflammatory messenger substances prevent the immune response from calming down, as happens in healthy people. The immune system remains in a persistently active state. Environmental factors Environmental factors can play a role in the development and progression of Crohn's disease. Although the exact causes of Crohn's disease are not yet fully understood, studies have shown that several factors may contribute to this condition: ⎯⎯• Smoke Smoking is a known risk factor for Crohn's disease. Studies have shown that smokers are almost twice as likely to develop Crohn's disease and that smoking can worsen the disease. ⎯⎯•Altered intestinal flora A disturbed intestinal flora, i.e. the microbial balance in the intestine, can play a role in the development of Crohn's disease. Studies show that certain bacterial strains are more common in people with Crohn's disease and that the intestinal flora can become unbalanced ⎯⎯•Nutrition Although no specific diet has been identified as a cause of Crohn's disease, there is evidence that a Western diet high in saturated fat, sugar, and processed foods may increase the risk of Crohn's disease. A low-fiber diet could also play a role. ⎯⎯•Environmental toxins It is thought that certain environmental toxins such as pesticides, chemicals and heavy metals may play a role in the development of Crohn's disease. Studies have shown that people living in developed countries are more likely to be affected by the disease. ⎯⎯•Psychological stress Although psychological stress is not the direct cause of Crohn's disease, stress and emotional stress can worsen the course of the disease and trigger flare-ups. It is important to note that these environmental factors do not affect all people with Crohn's disease equally. The exact connections and individual triggers can vary from person to person. Symptoms of Morbus Crohn Morbus Crohn often begins gradually. The disease progresses in episodes and symptoms can flare up and subside again and again. The most common symptoms are: ⎯⎯• Crampy abdominal pain ⎯⎯• Chronic diarrhea (sometimes with ⎯⎯• Blood in the stool when the colon is severely affected ⎯⎯• Fever ⎯⎯• nausea ⎯⎯• Vomit ⎯⎯• Loss of appetite ⎯⎯• weight loss If Crohn's disease has been present for a long time, not only the intestine is often affected, but also other organs. Possible symptoms are then: ⎯⎯• skin rash ⎯⎯• Joint pain and swelling ⎯⎯• Red eyes ⎯⎯• Liver and gallbladder problems ⎯⎯• Sore spots on the anus, sometimes also anal fissures Treatment of Morbus Crohn The Treatment for Morbus Crohn usually involves a combination of medications and lifestyle changes. Medications used to treat Crohn's disease include anti-inflammatory medications such as corticosteroids, immunosuppressants, and biologics. Additionally, making changes to dietary habits, avoiding certain foods, and taking supplements can help improve symptoms. In some cases, surgery may be necessary to prevent complications such as intestinal obstruction, fistulas or abscesses. However, when deciding to have surgery, people usually try to preserve the intestines as much as possible and only remove the affected areas. It is important to note that Crohn's disease is a chronic disease and there is no cure. Treatment aims to control symptoms, achieve remissions and slow disease progression to improve patients' quality of life. INUSpheresis® INUSpheresis® for Morbus Crohn INUSpheresis® is a special blood plasma purification therapy that can be used for various diseases, including Crohn's disease. This therapy can help to specifically remove inflammatory substances, immune complexes, autoantibodies and harmful substances from the blood. By using innovative filters, the healthy components of the blood are preserved. The aim of therapy is to effectively alleviate chronic inflammation and the associated symptoms by washing out the corresponding inflammatory mediators and immune complexes. After INUSpherese® treatment, a significant reduction in inflammatory messengers such as CRP or TNF-a can be detected in the blood. ELLANN® is one of the few certified centers in Germany that offer INUSpherese® therapy. It is important to us to provide our patients with the best possible support in freeing their bodies from stress that causes illness and thus promoting their health. Chronic inflammation INUSpheresis Details Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

ELLANN® - Das neue INUSpherese® Zentrum in Berlin. Ganzheitliche Entgiftung und Komplementärmedizin bei Umweltbelastungen, Autoimmunerkrankungen, Post-COVID und weiteren Erkrankungen. Homepage / Diseases Autoimmune diseases Chronic inflammation Long Covid Metabolic diseases Environmental diseases Diseases AUTOIMMUNE DISEASES LEARN MORE CHRONIC INFLAMMATION LEARN MORE LONG–COVID LEARN MORE METABOLIC DISEASES LEARN MORE ENVIRONMENTAL DISEASES LEARN MORE

Die INUSpherese® ist eine innovative Methode zur Reinigung des Blutplasmas. Das intelligente Filtersystem der INUSpherese® ist darauf ausgelegt, Umweltgifte, Autoantikörper, Immunkomplexe und Entzündungsmediatoren schonend zu entfernen. INUSpheresis® Homepage / Treatments / INUSpheresis® INUSpheresis® is an innovative method for purifying blood plasma. The intelligent filter system of INUSpherese® is designed to gently remove environmental toxins, autoantibodies, immune complexes and inflammatory mediators. The therapeutic benefits of INUSpherese® lie in its ability to support the immune system and activate the body's natural self-healing powers. It does this by effectively removing harmful substances that could otherwise stress the immune system and affect overall health. INUSpherese® can be easily integrated into holistic medicine as it is a gentle method for blood purification. It can be used as a standalone treatment or in conjunction with other therapeutic approaches to support and strengthen the body on a holistic level. INUSpheresis® Effectiveness and study situation Our medical team at ELLANN® consists of highly qualified and compassionate professionals who are passionate about your well-being. Each team member brings unique skills and experience to provide you with personalized, comprehensive care. Studies & News During INUSpheresis®, the patient's blood is drained from the body and passed through a special filter that can efficiently remove harmful substances and pro-inflammatory proteins. During the process, the blood is broken down into its main components so that the harmful substances can be selectively removed. The healthy blood components, including vital proteins, electrolytes and antibodies, are returned to the body. This selective process distinguishes INUSpheresis® from other blood purification procedures. During INUSpheresis®, an osmotic effect is created that makes it possible to remove pathogens not only from the blood, but also from the connective tissue, fatty tissue, nerve tissue, the eyes and all internal organs. How INUSpherese® works Difference from therapeutic apheresis INUSpheresis® represents a further development of therapeutic apheresis, although it is based on similar principles. Special filters with intelligent membranes and a specially designed device can also be used to specifically treat diseases for which apheresis has not previously been used. This technical adaptation offers numerous advantages, in particular more efficient filtration of harmful proteins and toxins. With the INUSpherese® does not occurExchange of blood plasma , as in plasmapheresis. During plasmapheresis, the exchanged plasma is replaced either with a protein solution (human albumin) or the plasma from healthy donors. In contrast to many other blood purification procedures, INUSpheresis® retains important proteins, electrolytes and antibodies in the blood. This ensures that the body is optimally supplied during treatment and does not lose any vital nutrients. INUSpheresis® differs fundamentally from dialysis, which is a proven method for removing urinary substances in patients with impaired kidney function. In contrast, INUSpheresis® is used to eliminate misdirected autoimmune antibodies, inflammatory messengers and environmental toxins, strengthen the immune system and reduce inflammatory processes. While dialysis is primarily used for patients with kidney problems, INUSpheresis® can help a broader group of patients struggling with autoimmune diseases, chronic inflammation, environmental stresses and long-COVID. Difference from dialysis What is filtered? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. This includes: ⎯⎯• Lipids and lipoprotein-a ⎯⎯• Pathogenic proteins ⎯⎯• Paraproteins ⎯⎯• Pathoproteins, haptens ⎯⎯• Pathogenous antibodies, auto-antibodies ⎯⎯• Tumor-associated proteins ⎯⎯• Circulating immune complexes ⎯⎯• Inflammatory substances (e.g. CRP, TNF-a) ⎯⎯• Toxic substances (environmental toxins) ⎯⎯• Heavy metals ⎯⎯• Pesticides ⎯⎯• Fungicides ⎯⎯• Microplastics Double plasma filtration and the use of intelligent filters make it possible to specifically wash out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect vaccination protection because antibodies and immune cells that are responsible for vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. The "INUS TKM58" secondary filter has an immunological membrane with fine pores and a special structure that is designed to specifically eliminate pathogenic proteins and toxic substances bound to proteins. The TKM58 works by filtering according to size, shape and weight. The secondary filter "INUS-30" is a lipid filter and is used in patients with hypercholesterolemia. In contrast to conventional filters, INUSpherese® uses finer pore filters. This makes it possible to remove up to 80% of lipids from blood plasma, which leads to improvement of microcirculation and reduction of inflammatory markers and fibrinogen. The INUS filters are disposable filters. Diagnosis A careful diagnosis at the beginning of every treatment is like a guide for our doctors and therapists. It makes it possible to identify the causes of the symptoms and, based on this, to design an individually tailored treatment strategy. An accurate diagnosis is essential as it lays the foundation for effective therapy aimed at providing you with the best possible help and promoting your well-being. Excerpt from the ELLANN® diagnostics offering: ⎯⎯• Laboratory analysis ⎯⎯• Eluate analyses ⎯⎯• ECG ⎯⎯• Darkfield diagnostics Access to ELLER KELLERMANN's extensive range of diagnostics, such as: ⎯⎯• Microbiome analysis ⎯⎯• Ultrasound examination ⎯⎯• X-ray diagnostics ⎯⎯• MRI diagnostics ⎯⎯• VNS analysis (vegetative nervous system) ⎯⎯• Bioimpedance analysis ⎯⎯• Spectrophotometry Our dedicated and knowledgeable medical team is dedicated to supporting your health and helping you on your road to recovery TEAM Indications Who is INUSpheresis® suitable for? Rheumatoid arthritis Hashimoto's thyroiditis Multiple Sclerosis (MS) Polyneuropathy (PNP) Autoimmune diseases Chronic inflammation Long Covid Metabolic diseases Environmental diseases Alzheimer dementia syndrome Lyme disease (Lyme disease) Chronic Fatique Syndrome (CFS) Chronic hepatitis C (health insurance benefit in Japan) Ulcerative colitis Crohn's disease Post Vacc Syndrome Familial hypercholesterolemia Multiple Chemical Hypersensitivity Syndrome (MCS) Toxicant-Induced Loss of Tolerance (TILT) INUSpheresis® is of particular importance for people who suffer from chronic illnesses or environmental stress, as it can help alleviate symptoms and significantly increase the quality of life of those affected. Below we provide a brief overview of the diseases we treat most frequently: AUTOIMMUNE DISEASES LEARN MORE CHRONIC INFLAMMATION LEARN MORE LONG–COVID LEARN MORE METABOLIC DISEASES LEARN MORE ENVIRONMENTAL DISEASES LEARN MORE Who is INUSpheresis® not suitable for? INUSpheresis® is an advanced therapy method that has the potential to improve the quality of life of many patients. Nevertheless, it should be noted that, as with any medical treatment, individual patient conditions must be taken into account as they can influence the applicability and effectiveness of the therapy. The following are specific health conditions for which the use of INUSpherese® should be considered particularly carefully in consultation with the medical team: ⎯⎯• Acute fever or inflammatory processes ⎯⎯• Recent strokes ⎯⎯• Acute heart disease ⎯⎯• Organ failure ⎯⎯• Advanced cancers ⎯⎯• Psychiatric disorders, including psychoses or anxiety neuroses ⎯⎯• Multimorbidity (the presence of multiple serious illnesses) This serves as a guide for a comprehensive discussion between patients and our ELLANN® medical team. The joint discussion allows the treatment plan to be adjusted according to the individual health conditions of the patient, with the ultimate goal always being to achieve the best possible health outcome for each patient. Despite the low side effects that INUSpheresis® brings with it compared to other invasive procedures, we are fully aware of our responsibility towards our patients. Our goal is for you to feel safe and secure throughout the entire treatment process. That's why every INUSpheresis® is personally accompanied and monitored by Ms. Kellermann, a specialist in anesthesiology and intensive care medicine. The fact that all INUSpherese® treatments are carried out under the continuous supervision of an intensive care doctor is a special feature that distinguishes ELLANN® from other centers. Because the well-being and safety of our patients are our top priority. Safety and side effects Ms. Kellermann, specialist in anesthesiology and intensive care medicine Process of the INUSpherese® treatment The INUSpherese® treatment takes place in our specially equipped rooms, which are designed for optimal outpatient treatment. The therapy is carried out in a pleasant and relaxed atmosphere. The treatment itself is gentle and painless. Preparation for INUSpheresis® Before INUSpheresis® is carried out, a thorough anamnesis and diagnosis is necessary. It may be useful to check certain laboratory parameters to determine whether this therapy is recommended for you. These include classic laboratory values such as CRP, erythrocyte sedimentation rate, interleukin 16 and 8 and tumor necrosis factor. You can find out more about our laboratory standards under Diagnostics and in a personal consultation. The day before treatment No special preparations are required before an INUSpherese® treatment. You can eat and exercise as usual. It is recommended to drink sufficient fluids the day before treatment, ideally around 3 liters. On the day of treatment On the day of INUSpheresis® You are advised to have a good breakfast and stop drinking about 2 hours before treatment to avoid going to the toilet during treatment. During treatment At the beginning of the procedure, infusion lines are inserted into the right and left armpits. During therapy, the blood from one arm passes through the filter system of a special INUS machine. The blood first passes through the first filter, which separates the solid blood components from the plasma. The solid components enter an air trap that ensures that no air is returned to the patient. The plasma is then passed through the secondary filter, where it is filtered using special membranes. Contaminants accumulate inside the filter while the cleaned plasma is pushed out through the membrane. The filtered plasma is then heated by a heater and reunited with the solid blood components from the air trap before finally being directed back into the body via the other armpit. The filtered pollutants are transported further from the second filter and collected in a bag (eluate) so that they can later be examined in a medical laboratory. The INUS device is equipped with state-of-the-art sensors and controls that precisely monitor and adjust the process. The complete INUSpherese® treatment usually lasts between 2 and 3 hours. During this time, our patients are continuously monitored technically and personally. After treatment After the INUSpherese® treatment, it is important to drink enough fluids to hydrate the body. It is recommended to drink plenty of water to replenish fluid loss. In addition, it is advisable to eat a balanced meal to provide the body with the necessary nutrients. It is recommended to avoid fatty or heavy meals as these can put a strain on digestion. Instead, easily digestible foods like fruits, vegetables, whole grains, and lean proteins can be good choices. However, it is always best to follow the specific recommendations of your doctor or healthcare professional as they can provide the most accurate information for your individual case. INUSpherese® is an extremely gentle treatment method with almost no side effects. Since it is still considered a minimal procedure, we recommend not driving a motor vehicle or bicycle on the day of treatment or for the following 24 hours. At the patient's request or on medical advice, the eluate (the liquid with residues filtered out) is sent for laboratory medical analyzes in order to determine the amounts of pollutants and pathogenic plasma residues that have been excreted. The cost of the laboratory test varies depending on the type of analysis desired and is discussed in advance with the patient. Particularly in the case of certain underlying diseases, these results are used to monitor the course of treatment and further therapy planning. Bei welchen Diagnosen kann die INUSpherese® helfen? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more Was genau wird bei der INUSpherese® gefiltert? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpherese® eine Blutwäsche? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. Wie viele INUSpherese® Behandlungen sind notwendig? The number of INUSpheresis® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. Was kostet eine INUSpherese® Behandlung? An INUSpheresis® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions Below you will find answers to common questions. Please note that individual consideration is required for each person. A personal consultation and a detailed anamnesis as well as therapy planning are essential.

News, Studien, Publikationen, Formulare und Patienteninformationen Homepage / Media Library Videos Podcasts & Interviews Patient information & forms Studies & publications News Media Library Studies & Publications Extracorporeal apheresis therapy for Alzheimer disease - targeting lipids, stress and inflammation. Stefan R. Bornstein, Karine Voit-Bak, Peter Rosenthal, Sergey Tselmin, Ulrich Julius, Ulrike Schatz, Bernhard O.Boehm, Sandrine Thuret, Gerd Kempermann, Heinz Reichmann, George P. Chrousos, Julio Licino, Ma-Li Wong, Andrew V. Schally (Nobel prize winner), Richard Straube, Mol Psychiatry, February 2020 Link to the study Long-COVID GerichtsurteilSozialgericht Landshut Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis Martin Achleitner, Charlotte Steenblock, Juliane Dänhardt, Natalia Jarzebska, Romina Kardashi, Waldemar Kanczkowski, Richard Straube, Roman N. Rodionov, Nitzan Bornstein, Sergey Tselmin, Frank Kaiser, Ronald Bucher, Mahmoud Barbir, Ma-Li Wong, Karin Voit-Bak , Julio Licinio & Stefan R. Bornstein, May 2, 2023, Molecular Psychiatry(2023) Study Link Die klinische Verbesserung von Long-COVID geht mit einer Verringerung von Autoantikörpern, Lipiden und Entzündungen nach therapeutischer Apherese einher. Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? Stefan R. Bornstein, Karin Voit-Bak, Timo DOnate, Roman N. Rodionov, Raul R. Gainetdinov, Sergey Tselmin, Waldemar Kanczowski, Gregor M.Müller, Martin Achleitner, Jun Wangm Julio Licino, Michael Bauer, Allan H. Young, Sandrine Thuret, Nicole Bechmann, Richard Straube, Mol Psychiatry, January 2022 Study Link Chronisches Post-COVID-19-Syndrom und chronisches Erschöpfungssyndrom (CFS): Spielt die extrakorporale Apherese eine Rolle? Is there a role for environmental and metabolic factors predisposing to severe COVID-19? Stefan R. Bornstein, Karin Voit-Bak, Henning Morawietz, Alexander Benjamin Bornstein, Waldimir Balanzew, Ulrich Julius, Roman N.Rodionov, Anne Maria Biener, Jun Wang, Klaus Martin Schulte, Peter Krebs, Günter Vollmer, Richard Straube, Horm Metab Res, July, 2020 Link to the study Spielen Umwelt- und Stoffwechselfaktoren eine Rolle bei der Veranlagung zu schwerem COVID-19? Changes in Water Properties in Human Tissue after Double Filtration Plasmapheresis—A Case Study. Felix Scholkmann, Roumiana Tsenkova, Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland, Aquaphotomics Research Department, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan, Molecules 2022, 27(12), 3947; Received: 18 May 2022 / Revised: 8 June 2022 / Accepted: 10 June 2022 / Published: 20 June 2022 Link to the study Änderungen der Wassereigenschaften in menschlichem Gewebe nach Plasmapherese mit doppelter Filtration – eine Fallstudie Lipid profiles in Lyme Borreliosis: A potential Role for Apheresis? Richard Straube, Karin Voit-Bak, A.Gor, Til Steinmeier, George P. Chrousos, Bernhard Otto Boehm, Andreas L. Birkenfeld, Mahmoud Barbir, Wladimir Balantsew, Stefan R.Bornstein, Horm Metab Res, May 2019 Link to the study Lipidprofile bei Lyme-Borreliose: Eine mögliche Rolle für die Apherese? Particles in the Eluate from Double Filtration Plasmapheresis—A Case Study Using Field Emission Scanning Electron Microscopy/Energy-Dispersive X-ray Spectroscopy (FE-SEM/EDX) Felix Scholkmann, Antonietta M. Gatti,MDPI, December 2022 Link zur Studie Partikel im Eluat nach Doppelfiltrationsplasmapherese - eine Fallstudie unter Verwendung von Feldemissions-Rasterelektronenmikroskopie/ Energiedispersiver Röntgenspektroskopie (FE-SEM/EDX) Human health concerns regarding microplastics in the aquatic environment - From marine to food systems Zhihao Yuan, Rajat Nag, Enda Cummins,ScienceDirect, June 2022 Link to the study Bedenken hinsichtlich der menschlichen Gesundheit in Bezug auf Mikroplastik in der aquatischen Umwelt - vom Meer bis zu Lebensmittelsystemen Precision Medicine Approach for Cardiometabolic Risk Factors in Therapeutic Apheresis Yin X, Takov K, Straube R, Voit-Bak K, Graessler J, Julius U, Tselmin S, Roman N Rodionov, Barbir M, Walls M, Theofilatos K, Mayr M , S.R. Bornstein,Thieme, 2022 Link to the study Präzisionsmedizinischer Ansatz für kardiometabolische Risikofaktoren in der therapeutischen Apherese Extracorporeal apheresis therapy for Alzheimer disease - targeting lipids, stress and inflammation. Stefan R. Bornstein, Karine Voit-Bak, Peter Rosenthal, Sergey Tselmin, Ulrich Julius, Ulrike Schatz, Bernhard O.Boehm, Sandrine Thuret, Gerd Kempermann, Heinz Reichmann, George P. Chrousos, Julio Licino, Ma-Li Wong, Andrew V. Schally (Nobel prize winner), Richard Straube, Mol Psychiatry, February 2020 Link to the study Extrakorporale Apherese-Therapie bei Alzheimer-Krankheit - Lipide, Stress und Entzündungen im Visier. Patient information about INUSpherese® File Name Description Size Download Information sheet INUSpherese® Download as an editable PDF 546KB INUSpheresis® information sheet fillable PDF file 531KB General patient information Download as an editable PDF 41KB General patient information fillable PDF file 39KB Health questionnaire Download as an editable .pdf 1MB Health check-up sheet fillable PDF file 2.1MB Inguinal catheter information sheet Download as an editable .pdf 608KB Information sheet inguinal catheter.pdf fillable PDF file 603KB Treatment contract Download as an editable .pdf 510KB Treatment contract fillable PDF file 508KB Podcasts & Interviews Inuspheresis vs. other apheresis procedures: Why research and safety are crucial | QS24 Dr. med. univ. Birgit Bernadette Heinisch-Röchert, Medical Director Karin Bak, CEO of INUS Medical Center AG Moderation: Alexander Glogg Interview Inuspheresis vs. other apheresis procedures: Why research and safety are crucial | QS24 Dr. med. univ. Birgit Bernadette Heinisch-Röchert, Medical Director Karin Bak, CEO of INUS Medical Center AG Moderation: Alexander Glogg Interview Inuspheresis vs. other apheresis procedures: Why research and safety are crucial | QS24 Dr. med. univ. Birgit Bernadette Heinisch-Röchert, Medical Director Karin Bak, CEO of INUS Medical Center AG Moderation: Alexander Glogg Interview Videos Videos PFAS / Toxic chemical in Germany _ ARD reporting Link to video Bloodcleanse after chemotherapy _ Bild reporting Link to video 'Detox for the blood". _ Elle article Link to video

ELLANN® - Das neue INUSpherese® Zentrum in Berlin. Ganzheitliche Entgiftung und Komplementärmedizin bei Umweltbelastungen, Autoimmunerkrankungen, Post-COVID und weiteren Erkrankungen. Text und Konzept, www.slyhealth.com, Branding, Konzept und Development, www.studionoseven.com, Heike Forbrig-Demke PART OF Imprint Address: ELLANN® c/o INUSpheresis Center Berlin GbR Leipziger Platz 15 10117 Berlin Germany Shareholder: Prof. Dr. med. Gerhard Eller Prof. Dr. med. Ivan Kellerman Managing directors: Stefanie Hladitsch Medical administration: Dr. med. Birgit Bernadette Heinisch-Röchert Medical Association: Berlin Medical Association Friedrichstrasse 16, 10969 Berlin www.aekb.de Professional regulations: Professional regulations for doctors in Berlin Responsible for content according to § 5 MDStV/TDG: Prof. Dr. med. Gerhard Eller, MBA, MSc. Prof. Dr. med. Ivan Kellerman Text and concept www.slyhealth.com Branding, concept and development www.studionoseven.com Heike Forbrig-Demke Limitation of Liability: The contents of this website are created with utmost care. However, the provider assumes no liability for the accuracy, completeness and topicality of the content provided. The use of the contents of the website is at the user's own risk. Contributions marked by name reflect the opinion of the respective author and not always the opinion of the provider. The mere use of the provider's website does not create any contractual relationship between the user and the provider. External links: This website contains links to third-party websites (“external links”). These websites are the responsibility of the respective operators. When the external links were first linked, the provider checked the external content to see whether there were any legal violations. At the time, no legal violations were apparent. The provider has no influence on the current and future design or content of the linked pages. Setting external links does not mean that the provider adopts the content behind the reference or link as its own. It is unreasonable for the provider to constantly monitor external links without concrete evidence of legal violations. However, if we become aware of legal violations, such external links will be deleted immediately. Copyright and ancillary copyrights: The content published on this website is subject to German copyright and ancillary copyright law. Any use not permitted by German copyright and ancillary copyright law requires the prior written consent of the provider or respective rights holder. This applies in particular to the reproduction, editing, translation, storage, processing or reproduction of content in databases or other electronic media and systems. Contents and rights of third parties are marked as such. The unauthorized reproduction or distribution of individual content or entire pages is not permitted and is punishable by law. Only the production of copies and downloads for personal, private and non-commercial use is permitted. The display of this website in external frames is only permitted with written permission.

Die Multiple Sklerose ist eine autoimmune, chronisch-entzündliche Erkrankung des zentralen Nervensystems. Bei der MS greift das Immunsystem fälschlicherweise die Nerven im Gehirn und Rückenmark an und schädigt diese. Das Wort Sklerose bedeutet Narbenbildung. Es entstehen „Narben auf Nerven“, wodurch diese nicht mehr richtig arbeiten können. POLYNEUROPATHY Homepage / Diseases / Autoimmune Diseases / Polyneuropathy Polyneuropathy (PNP), also called peripheral neuropathy, is a disorder that affects the peripheral nerves in the body. Peripheral nerves are the nerves that lie outside the brain and spinal cord. They are responsible for transmitting sensory information (sensory information) from the body's organs, muscles and skin to the central nervous system and for conducting motor signals from the central nervous system to the muscles. When these nerves are damaged or destroyed, it can cause various symptoms such as numbness, tingling, weakness and pain in the affected areas. Polyneuropathy Causes of polyneuropathy Causes of polyneuropathy Polyneuropathy can occur acutely (with a sudden onset) or chronically (slow development, often over a long period of time). Causes of acute polyneuropathy In acute polyneuropathy, the trigger is, for example, an infection with poison-producing bacteria, such as diphtheria. An autoimmune reaction (when the body's own tissues are attacked), such as in Guillain-Barré syndrome or certain toxins, among others. Tricresyl phosphates or thallium can be the trigger. Causes of chronic polyneuropathy The cause of chronic polyneuropathy is often unknown. The most common known causes include diabetes and excessive alcohol consumption. Experts estimate that one in two diabetics will develop diabetic polyneuropathy during their lifetime. The reason for this is not yet completely clear. However, it is suspected that the increased blood sugar plays a significant role and promotes nerve damage. In polyneuropathy as a result of chronic alcohol abuse, the nerves are toxically damaged and the conduction of stimuli is thereby disrupted. Vitamin and nutrient deficiencies Other causes of PNP can include vitamin B12 deficiency, which leads to spinal cord damage known as funicular myelosis and often pernicious anemia. Likewise, other nutritional deficiencies such as a lack of thiamine (vitamin B1) or, in rare cases, excessive intake of vitamin B6 (pyridoxine) can also contribute to PNP. Genetic predisposition There is a genetic predisposition to polyneuropathy. Charcot-Marie-Tooth disease (CMT), also known as hereditary motor and sensory neuropathy (HMSN), is the most common form of hereditary neuropathy with an incidence of approximately 1 in 2,500. Other causes of polyneuropathy: Infections (such as hepatitis C, HIV infection, Lyme disease, shingles) and chronic autoimmune diseases (such as chronic inflammatory demyelinating polyneuropathy, vasculitis and systemic lupus erythematosus ) can be considered as the cause of PNP. Cancer diseases (e.g. multiple myeloma), can also trigger PNP when the cancer invades the nerves directly or puts pressure on the nerves, thereby damaging the nerves. In this context it should also be mentioned thatDrug, et al. The antiepileptic drug phenytoin, some antibiotics (chloramphenicol, nitrofurantoin and sulfonamides) and some chemotherapy agents (vinblastine and vincristine) can trigger PNP, which is noted under side effects in the package leaflet. OneHypothyroidism (hypothyroidism), but also kidney failureToxins , among othersHeavy metals such as arsenic, lead and mercury can be the cause of PNP. Symptoms of polyneuropathy Depending on the cause, the symptoms of polyneuropathy can appear suddenly (acute, over a few days to a few weeks) or they develop slowly and occur over a longer period of time (chronic, over months or years). Symptoms of acute polyneuropathies (as in Guillain-Barré syndrome or in connection with toxins) ⎯⎯• suddenly loss of sensation in both legs and rapidly progressing to the arms ⎯⎯• Weakness ⎯⎯• Tingling or loss of sensation, including in the respiratory muscles, which can lead to respiratory failure Symptoms of chronic polyneuropathies ⎯⎯• Sensation disorders such as tingling, burning and “pins and needles” as well as pain in the affected areas of the body, often initially in the feet ⎯⎯• Unsteady gait ⎯⎯• Muscle weakness and muscle breakdown Symptoms of diabetic neuropathy ⎯⎯• Painful tingling or burning in the hands and feet – distal polyneuropathy ⎯⎯• Loss of temperature and pain sensation (risk of burning yourself) ⎯⎯• Loss of pain sensations that warn of excessive stress; Result in frequent injuries to the joints. This type of joint damage is called neurogenic arthropathy (Charcot joints ). ⎯⎯• Disturbances in autonomic nervous system , which regulates automatic body functions such as blood pressure, heartbeat, bladder and bowel function. Typical complaints are: Constipation Disturbance of sexual function Fluctuations in blood pressure – the most noticeable is a sudden drop in blood pressure when standing up pale and dry skin less sweating Loss of bladder and bowel control Symptoms of hereditary polyneuropathies (like Charcot-Marie-Tooth-Hoffmann syndrome) ⎯⎯• Hammertoes ⎯⎯• Hollow foot ⎯⎯• Curved spine (scoliosis) ⎯⎯• Unusual sensory sensations and muscle weakness are usually only mild ⎯⎯• Patients with mild symptoms may not even notice them or pay them no attention. Other patients are severely affected. Treatment options for polyneuropathy When treating polyneuropathy, it is important to address the underlying cause. In the case of diabetic polyneuropathy, good blood sugar control is crucial to prevent further nerve damage. A slow reduction in blood sugar levels over a period of three months is recommended. In the case of alcohol-related polyneuropathy, avoiding alcohol is crucial. Taking vitamin B1 can also help regenerate nerves. There are several treatment options that can help relieve symptoms and slow the progression of the disease. Some therapies and treatment options include: Medication Various medications can treat pain, inflammation, or nerve damage. These include painkillers, antidepressants, anticonvulsants and, in some cases, injections. physical therapy Physical therapy can help improve muscle strength, maintain mobility, and manage balance problems. Occupational therapy Through specific exercises and techniques, occupational therapy can help manage daily activities and improve quality of life. Transcutaneous electrical nerve stimulation (TENS) This method uses electrical impulses to relieve pain by stimulating the nerves acupuncture This alternative treatment method can help relieve pain and improve well-being. INUSpheresis® INUSpherese® as an accompanying therapy option for MS INUSpheresis® shows a clear evidence-based indication in the treatment of polyneuropathy, as it effectively filters out inflammation-causing agents from the blood and ultimately also the nervous system. INUSpheresis® is based on the process of apheresis or blood washing, in which harmful substances such as toxins, heavy metals, pesticides and other unwanted compounds are removed from the blood. INUSpheresis makes it possible to effectively remove pathological proteins, immune complexes, metabolic waste products, infectious toxins, allergens and inflammatory messengers from the body. The exact way INUSpherese® works is based on the use of special intelligent filter systems that specifically filter pathogenic substances from the blood while protecting vital blood cells and proteins. INUSpheresis® can be used for chronic inflammation, metabolic and immune system diseases, such as: B. autoimmune diseases can be used. It is important to point out that the INUSpherese® In the case of chronic polyneuropathy, it is not the causal treatment, but rather a complementary measure to detoxify the body and support recovery. An exact number of required INUSpherese® Treatments may vary from case to case. However, it should be noted that INUSpheresis® is a medical procedure and may only be performed by qualified professionals. In Germany there are only a few centers that offer this technology, mostly in combination with other holistic therapeutic approaches. ELLANN®, as a certified INUS partner, specializes in INUSpheresis to help you free the body of toxic stress and improve long-term health. doctors INUSpheresis Details A study published in 2019 looks at the use of INUSpheresis® in diabetic neuropathy and other peripheral neuropathies. This study examined the effectiveness of INUSpheresis in removing metabolic, inflammatory, immunological, and environmental factors that may contribute to the development of diabetic neuropathy. The authors note that therapeutic apheresis (INUSpherese®) may be a promising treatment option. Study situation study Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Die Lyme-Borreliose ist eine durch Zecken übertragene bakterielle Infektion. Die übertragenen Bakterien heißen Borrelien und gehören wie die Erreger der Syphilis zu der Bakterienfamilie der Spirochäten und sind wie eine unregelmäßige Spirale geformt, groß und beweglich.  BORRELIOSE (LYME-BORRELIOSE) Homepage / Diseases / Chronic inflammation / Borreliose (Lyme-Borreliose) Borreliose (Lyme-Borreliose) disease is a tick-borne bacterial infection. The transmitted bacteria are called Borrelia and, like the pathogens of syphilis, belong to the spirochete family of bacteria and are shaped like an irregular spiral, large and mobile. Lyme disease is an infectious disease caused by bacteria that is transmitted primarily through the bite of infected ticks. The bacteria, called Borrelia burgdorferi, can enter the body when an infected tick bites a person. The most common causes of Lyme disease are therefore the bite of ticks, especially ticks of the genus Ixodes, which carry the bacteria. Once the bacteria enter the body, they can spread to various organs and tissues, causing a variety of symptoms. Borreliose (Lyme-Borreliose) Symptoms of Borreliose Symptoms of Borreliose Lyme disease progresses in three stages: Early localized stage Early disseminated stage (widespread) Late stage There is usually a symptom-free period between the early and late stages. Stage 1 A large, raised red spot (erythema migrans) usually appears at the bite site. The spot appears in about 75 percent of people 3 to 32 days after the tick bite. As a rule, this spot slowly increases in size to a diameter of up to 50 cm, with the redness in the center of the spot usually subsiding. But the appearance can vary. The center can remain red, but multiple rings can also form around the reddened center (like a target). The stain usually disappears after 3 to 4 weeks. However, in about 25 percent of those infected, a red spot does not develop or is at least not noticed. Stage 2 This stage begins when the bacteria spread throughout the body. It can begin days to weeks after the spot first appears. It is therefore important to pay attention to possible symptoms. Common symptoms of early disseminated stage of Lyme disease: ⎯⎯• exhaustion ⎯⎯• Chills ⎯⎯• Fever ⎯⎯• Headache ⎯⎯• Stiff neck ⎯⎯• Muscle pain ⎯⎯• painful joint swelling These symptoms of Lyme disease can last for weeks. Almost half of those infected who are not treated develop additional, usually smaller, red spots on other parts of the body. These symptoms are often misinterpreted and mistaken for flu or normal viral infections, especially when erythema migrans is not present. The nervous system is affected in around 15 percent of patients. The most common complications are meningitis and facial paralysis. Stage 3 If the initial infection is left untreated, further symptoms can often occur months or years later. Typical late-stage symptoms include: ⎯⎯• Lyme arthritis: Intermittent or chronic inflammation of the joints that affects one or more joints. In most cases the knee joints are affected. There is also pain in the tendons and muscles. ⎯⎯• Skin appearance: The skin on the feet and hands becomes bluish and very thin. ⎯⎯• Nerves: These can be further damaged. In severe cases, parts of the body are paralyzed. ⎯⎯• Chronic fatigue ⎯⎯• Character changes ⎯⎯• Mood swings In the worst case scenario, untreated Lyme disease can be fatal. Therapy for Borreliose Treatment for Lyme-Borreliose usually includes antibiotics, which are prescribed depending on the stage of the disease. Cases detected early can often be treated with two to four weeks of antibiotic therapy. In advanced cases, where the disease has spread further or complications have already arisen, longer antibiotic therapy may be necessary. It is important that treatment begins as soon as possible after diagnosis to reduce the risk of long-term effects. INUSpheresis® INUSpherese® for Lyme-Borreliose Borreliose has complex effects on the body. New research suggests that lipid metabolism may play a crucial role in this disease. Bacteria such as Borrelia burgdorferi are able to use the host organism's fats to survive and spread within the body. This could be why patients with Lyme disease often have altered lipid profiles, including elevated lipid levels. This suggests that elevated lipid levels may be contributing to Lyme disease persisting and causing serious complications. A pilot study examined the role of circulating lipids and lipoproteins in Lyme disease patients and observed the effects of extracorporeal double membrane filtration (INUSpheresis®) on disease progression. The lipid profiles of the subjects with Borrelia infection were analyzed before and after the use of INUSpheresis®. It was found that after INUSpheresis® the concentrations of circulating lipids such as cholesterol, triglycerides, LDL, LP(a) and other inflammatory lipids decreased significantly. At the same time, disease symptoms and indicators of inflammation such as C-reactive protein (CRP) improved. Due to these promising results, we at ELLANN® offer INUSpheresis® as an accompanying therapy for Lyme disease. Study INUSpheresis Details Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions