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Chronic Diseases


Chronic Inflammation

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Borreliose (Lyme-Borreliose)

Borreliose (Lyme-Borreliose) disease is a tick-borne bacterial infection. The transmitted bacteria are called Borrelia and, like the pathogens of syphilis, belong to the spirochete family of bacteria and are shaped like an irregular spiral, large and mobile. 


Lyme disease is an infectious disease caused by bacteria that is transmitted primarily through the bite of infected ticks. The bacteria, called Borrelia burgdorferi, can enter the body when an infected tick bites a person. The most common causes of Lyme disease are therefore the bite of ticks, especially ticks of the genus Ixodes, which carry the bacteria.


Once the bacteria enter the body, they can spread to various organs and tissues, causing a variety of symptoms.

Borreliose (Lyme-Borreliose)

Chronical Inflammation

Symptoms of Borreliose

Symptoms of Borreliose

Lyme disease progresses in three stages:

  1. Early localized stage

  2. Early disseminated stage (widespread)

  3. Late stage


There is usually a symptom-free period between the early and late stages.

Stage 1

A large, raised red spot (erythema migrans) usually appears at the bite site. The spot appears in about 75 percent of people 3 to 32 days after the tick bite. As a rule, this spot slowly increases in size to a diameter of up to 50 cm, with the redness in the center of the spot usually subsiding. But the appearance can vary. The center can remain red, but multiple rings can also form around the reddened center (like a target). The stain usually disappears after 3 to 4 weeks. However, in about 25 percent of those infected, a red spot does not develop or is at least not noticed.

Stage 2

This stage begins when the bacteria spread throughout the body. It can begin days to weeks after the spot first appears. It is therefore important to pay attention to possible symptoms.

Common symptoms of early disseminated stage of Lyme disease:

⎯⎯•  exhaustion

⎯⎯•  Chills 

⎯⎯• Fever 

⎯⎯• Headache 

⎯⎯• Stiff neck

⎯⎯• Muscle pain 

⎯⎯• painful joint swelling 


These symptoms of Lyme disease can last for weeks. Almost half of those infected who are not treated develop additional, usually smaller, red spots on other parts of the body. These symptoms are often misinterpreted and mistaken for flu or normal viral infections, especially when erythema migrans is not present.

The nervous system is affected in around 15 percent of patients. The most common complications are meningitis and facial paralysis.

Stage 3

If the initial infection is left untreated, further symptoms can often occur months or years later. Typical late-stage symptoms include:


⎯⎯• Lyme arthritis: Intermittent or chronic inflammation of the joints that affects one or more joints. In most cases the knee joints are affected. There is also pain in the tendons and muscles.

⎯⎯• Skin appearance: The skin on the feet and hands becomes bluish and very thin.

⎯⎯• Nerves: These can be further damaged. In severe cases, parts of the body are paralyzed.

⎯⎯• Chronic fatigue

⎯⎯• Character changes

⎯⎯• Mood swings


In the worst case scenario, untreated Lyme disease can be fatal.

Therapy for Borreliose

Treatment for Lyme-Borreliose usually includes antibiotics, which are prescribed depending on the stage of the disease. Cases detected early can often be treated with two to four weeks of antibiotic therapy. In advanced cases, where the disease has spread further or complications have already arisen, longer antibiotic therapy may be necessary. It is important that treatment begins as soon as possible after diagnosis to reduce the risk of long-term effects.


ELLANN® Health I INUSpherese®

INUSpherese® for Lyme-Borreliose

Borreliose has complex effects on the body. New research suggests that lipid metabolism may play a crucial role in this disease. Bacteria such as Borrelia burgdorferi are able to use the host organism's fats to survive and spread within the body. This could be why patients with Lyme disease often have altered lipid profiles, including elevated lipid levels. This suggests that elevated lipid levels may be contributing to Lyme disease persisting and causing serious complications. A pilot study examined the role of circulating lipids and lipoproteins in Lyme disease patients and observed the effects of extracorporeal double membrane filtration (INUSpheresis®) on disease progression. 


The lipid profiles of the subjects with Borrelia infection were analyzed before and after the use of INUSpheresis®. It was found that after INUSpheresis® the concentrations of circulating lipids such as cholesterol, triglycerides, LDL, LP(a) and other inflammatory lipids decreased significantly. At the same time, disease symptoms and indicators of inflammation such as C-reactive protein (CRP) improved.


Due to these promising results, we at ELLANN® offer INUSpheresis® as an accompanying therapy for Lyme disease.

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  • ⎯⎯•  Allergies

    ⎯⎯•  Lyme disease

    ⎯⎯•  Chronic fatigue syndrome (CFS)

    ⎯⎯•  Chronic hepatitis C

    ⎯⎯•  Hashimoto

    ⎯⎯•  Hyperlipidemia

    ⎯⎯•  Crohn's disease

    ⎯⎯•  multiple sclerosis

    ⎯⎯•  Multiple Chemical Hyper-

                sensitivity syndrome (MCS)

    ⎯⎯•  Parkinson's

    ⎯⎯•  Post-COVID syndrome

    ⎯⎯•  Post-vac syndrome

    ⎯⎯•  Rheumatism (chronic inflammatory)

    ⎯⎯•  Heavy metal poisoning

    ⎯⎯•  and more

  • INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health.

  • INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. 

  • The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation.

  • An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals.

Frequently asked Questions

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