ELLANN® ist ein integraler Bestandteil der ELLER & KELLERMANN Privatpraxis. Mit der Eröffnung des ersten INUSpherese® Zentrums erweitern wir unser Angebot, um auf die steigende Nachfrage nach spezialisierten Entgiftungsverfahren und Therapien im Bereich der Umweltmedizin und Zivilisationskrankheiten zu reagieren. Homepage / About Us PART OF Since September 1, 2023, ELLANN® has been welcoming you to an environmentally friendly practice that was designed according to ecological principles and covers a generous 360 square meters. The bright and modern ambience offers an impressive panoramic view of Potsdamer Platz, creates a unique atmosphere and invites you to feel good. Our practice was developed specifically for the needs of INUSpherese® and is equipped with state-of-the-art and comfortable therapy tables. We also offer separate treatment cabins and a VIP cabin for an exclusive treatment experience. ELLANN® is an integral part of ELLER & KELLERMANN private practice. With the opening of the first INUSpherese® center, we are expanding our offering in order to respond to the increasing demand for specialized detoxification procedures and therapies in the field of environmental medicine and lifestyle diseases. About Us team Our medical team at ELLANN® consists of highly qualified and compassionate professionals who are passionate about your well-being. Each team member brings unique skills and experience to provide you with personalized, comprehensive care. Dr. med. Birgit Bernadette Heinisch-Röchert Medical Director ELLANN® The medical director of ELLANN®, Dr. med. Birgit Heinisch-Röchert, is a specialist in internal medicine and has acquired her extensive expertise during her many years at the University Hospital Vienna. Her knowledge extends from intensive care medicine to clinical pharmacology and is characterized by her strong commitment to the well-being of her patients. But Dr. Heinisch-Röchert does not limit herself to conventional medical practices. She has continuously expanded her specialist knowledge and dealt intensively with orthomolecular medicine, evidence-based complementary medicine and the broad spectrum of functional medicine. Particularly noteworthy is her efforts in the research and development of innovative and effective long-COVID therapies. Her comprehensive expertise and interdisciplinary approach enable her to create personalized therapy concepts with her patients in mind. Her tireless commitment, her empathetic manner and her high level of professional competence make her an extremely valued medical advisor. Galina Kellerman Medical management of anesthesia and emergency medicine Ms. Kellermann, a former senior physician in anesthesiology and intensive care medicine, uses her many years of professional experience to ensure comprehensive care, even in emergencies. Their exceptional expertise ensures we can provide world-class patient care, even in complex and demanding medical scenarios. The focus of our work at ELLANN® is the well-being and safety of our valued patients. An outstanding differentiation from many other centers is the ongoing presence of Ms. Kellermann during the INUSpherese® treatment. At ELLANN® we combine medical excellence with a strong focus on emergency medicine. The result is comprehensive, safe and extremely professional support that you can rely on in every situation. Carla Murguey Medical process manager and INUSpherese® training manager Ms. Murguey successfully completed her medical studies in Venezuela. After graduating, she specialized in emergency and general medicine and became involved in the field of psychotherapy, particularly in the integration of psychological and social support. Over the last few years, Ms. Murguey has acquired extensive knowledge and qualifications, particularly in the operation and use of INUS devices. Her training at the INUS Center in Cham led to the discovery of her passion for the technical aspects and treatment methods of INUSpheresis®️. As medical process manager and training manager at ELLANN®️, she made a significant contribution to the training of the team, monitored training, ensured treatment processes and ensured compliance with the highest quality standards. Carla Murguey represents a combination of professionalism and passion in her work. Sarah Kazalski Care and Onboarding Manager After over a decade in the fashion and media world and numerous international stays in global metropolises such as Paris, London and New York, Sarah decided to give her passion for medicine the space it deserves. It began its development beyond the boundaries of traditional human medicine many years ago when it dedicated itself intensively to those healing and therapeutic procedures that are often neglected in conventional medicine due to their unique and powerful mechanisms of action. After successfully completing her training as a health coach at the INN in New York, she returned to Germany. Here she successfully started her basic training as a medical assistant and is currently training to become a naturopath. Sarah's empathy, her fluent German and English skills and her dedication to INUSpheresis® make her the ideal contact for our national and international patient management at ELLANN®. She ensures that each of our patients receives comprehensive care from start to finish. With Sarah you can rest assured that you are in the best hands. Sarah Kazalski Care and Onboarding Manager After over a decade in the fashion and media world and numerous international stays in global metropolises such as Paris, London and New York, Sarah decided to give her passion for medicine the space it deserves. It began its development beyond the boundaries of traditional human medicine many years ago when it dedicated itself intensively to those healing and therapeutic procedures that are often neglected in conventional medicine due to their unique and powerful mechanisms of action. After successfully completing her training as a health coach at the INN in New York, she returned to Germany. Here she successfully started her basic training as a medical assistant and is currently training to become a naturopath. Sarah's empathy, her fluent German and English skills and her dedication to INUSpheresis® make her the ideal contact for our national and international patient management at ELLANN®. She ensures that each of our patients receives comprehensive care from start to finish. With Sarah you can rest assured that you are in the best hands. We are here for you We warmly invite you to get to know our dedicated team and our innovative practice in person. At ELLANN®, your health is our focus and we look forward to accompanying you on your path to holistic health. Contact us today to schedule a consultation. Our knowledgeable team is ready to answer all your questions and develop a tailored treatment strategy for you. We look forward to welcoming you and helping you achieve your health goals. Consultation appointment

Autoimmunerkrankungen resultieren aus einer fehlerhaften Funktion des körpereigenen Immunsystems, bei der es versehentlich körpereigene Zellen und Gewebe angreift, anstatt nur Krankheitserreger wie Bakterien und Viren zu bekämpfen. Es existieren zahlreiche verschiedene Arten von Autoimmunerkrankungen. LONG_COVID DISEASES Home / Diseases / Long-COVID Diseases After an acute COVID-19 infection, symptoms can persist for many months. This is then referred to as long COVID. Studies estimate that around 10-20% of people suffer from long COVID syndrome after a SARS-CoV-2 infection. In Germany, where more than 26 million people have been proven to have COVID-19 so far, this means that more than two to four million people could potentially be affected by Long COVID. The symptoms significantly affect the quality of life, including the need for care and early retirement, and they cannot be explained by other medical diagnoses Long-COVID Ddiseases fatigue Persistent exhaustion (fatigue) Muscles Diffuse muscle pain (myalgia) Mentally Depressive symptoms, anxiety Sleep Difficulty falling asleep and staying asleep immune system Autoimmunity, dysregulated immune system with excessive inflammatory reaction, recurring infections Organ dysfunction Heart, lungs, gastrointestinal tract, liver, kidneys Nervous system Inflammation, autoantibodies against binding sites of neurotransmitters (stimulation transmission from one nerve cell to another cell), tingling (paraesthesia), numbness (hypesthesia), concentration and memory disorders (brain fog) In a few cases, similar symptoms may also follow a COVID-19 vaccination occurs, which is called Post Vacc Syndrome referred to as. Causes of Long COVID 01 Immunological factors Autoimmune processes may be involved in the development of long-term consequences, i.e. the immune system is impaired and incorrectly recognizes the body's own structures as foreign. 02 Reactivated infections Multiple reactivations of “hidden”, so-called latent viruses, bacteria and Borrelia can cause various symptoms and confuse and weaken the immune system. 03 Change in blood flow Research has shown that COVID-19 can cause changes in blood flow and deformation of red blood cells, preventing them from passing through the smallest blood vessels called capillaries. These small vessels become blocked (microthrombi). 04 Combined mechanisms As a rule, there is a combination of different factors that need to be deciphered and resolved. Thanks to intensive research, new findings are continually being added. It is important to note that autoimmune diseases can vary widely and not all of these factors play a role in every case. The exact cause can vary from disease to disease. Causes of Long COVID The exact causes are still unclear and there is currently no standardized and rational diagnostic method, such as laboratory tests. Therefore, there is no established treatment for Long COVID Syndrome. Based on the current state of research, it is assumed that several factors could play a role in the development of Long-COVID. These may include psychological factors such as stress and anxiety, a sustained inflammatory response in the body, and the following: Examples of autoimmune diseases Rheumatoide Arthritis Hashimoto-Thyreoiditis Colitis Ulcerosa Morbus Crohn Multiple Sklerose (MS) Polyneuropathie Rheumatoid arthritis Rheumatoid arthritis is an autoimmune disease in which the immune system attacks the joints. This leads to pain, inflammation and often joint deformation. Learn more Hashimoto's thyroiditis Hashimoto's thyroiditis is an autoimmune disease in which the immune system attacks the thyroid. This disrupts the thyroid's hormone production, leading to symptoms such as fatigue, weight gain and mood swings. Learn more Ulcerative colitis Ulcerative colitis is an autoimmune intestinal disease in which the immune system attacks the lining of the colon. This leads to inflammation, ulcers and symptoms such as diarrhea, abdominal pain and weight loss. Learn more Crohn's disease Crohn's disease is another inflammatory bowel disease in which the immune system attacks parts of the digestive tract. This can lead to severe abdominal pain, diarrhea, weight loss, and inflammation in various parts of the digestive tract. Learn more Multiple sclerosis (MS) MS is an autoimmune disease of the central nervous system in which the immune system attacks the protective layer of nerve fibers known as myelin. This leads to a variety of neurological symptoms such as muscle spasms, vision problems and weakness. Learn more Polyneuropathy Polyneuropathy is a group of autoimmune diseases in which the immune system attacks the peripheral nerves. This can cause symptoms such as numbness, tingling, muscle weakness and pain in the extremities. Learn more Causes of Long COVID Immunological factors Autoimmune processes may be involved in the development of long-term consequences, i.e. the immune system is impaired and incorrectly recognizes the body's own structures as foreign. Reactivated infections Multiple reactivations of “hidden”, so-called latent viruses, bacteria and Borrelia can cause various symptoms and confuse and weaken the immune system. Change in blood flow Research has shown that COVID-19 can cause changes in blood flow and deformation of red blood cells, preventing them from passing through the smallest blood vessels called capillaries. These small vessels become blocked (microthrombi). Combined mechanisms As a rule, there is a combination of different factors that need to be deciphered and resolved. Thanks to intensive research, new findings are continually being added. The exact causes are still unclear and there is currently no standardized and rational diagnostic method, such as laboratory tests. Therefore, there is no established treatment for Long COVID Syndrome. Based on the current state of research, it is assumed that several factors could play a role in the development of Long-COVID. These may include psychological factors such as stress and anxiety, a sustained inflammatory response in the body, and the following: INUSpheresis® INUSpherese® as a treatment option For patients suffering from severe long-COVID, ELLANN® uses INUSpheresis® as a combined therapy. It usually consists of two treatment cycles in which special filters are used. Which filter is used is decided individually depending on the symptoms, the course of the disease and the autoimmune antibody concentration in the blood. Read more about how it works and the two special filters INUS 30 and TKM58 under INUSpherese®. We create an individual therapy plan for each patient based on their health status and personal goals. INUSpheresis® is an essential component of our holistic therapy. Other methods such as interval hypoxia-hyperoxia therapy (IHHT), infusion concepts, systematic laser application, personalized nutrient therapy, osteopathic treatments for muscle pain, breathing techniques and diaphragm treatments can also be used. Find out more about this under Treatment. Treatment INUSpheresis Details We charge 2,218 euros per treatment cycle. The INUSpherese® costs are purely self-pay services, as the costs for this special therapy cannot be shown using GOÄ numbers. There are also costs for medical care before, during and after INUSpheresis®, laboratory costs and costs for individual infusion therapies. These are mapped via GOÄ and material cost blocks and can be submitted to private payers. Depending on the contractual relationship, up to 1,600 euros can be reimbursed by the respective private insurance company. Costs for laboratory tests are billed directly by the laboratory and are not included in the total cost pool. For an educational interview and twoINUSpheresis ® Treatments cost between 5,600 euros and 5,800 euros on average. Please feel free to contact us if you have any further questions about costs. Payments in installments are also possible at any time upon request. A recent court ruling from Landshut gives those affected cause for hope regarding financial support for this treatment. You can read this judgment here. Costs and reimbursement of the INUSpherese® treatment Long Covid court ruling In a recent study, specific biomarkers were analyzed before and after therapeutic apheresis in different groups (cohorts) of Long COVID patients. Patients who reported significant improvement after two cycles experienced significant decreases in neurotransmitter autoantibodies, lipids and inflammatory markers. In addition, a 70% reduction in fibrinogen was observed. Elevated fibrinogen levels can increase the risk of blood clots and cardiovascular disease. After apheresis, clumped red blood cells (erythrocyte rouleaux) and fibrin fibers also largely disappeared. These findings are extremely significant as it is the first study to demonstrate an association between specific biomarkers and clinical symptoms in Long COVID patients. In view of these results and our previous positive experiences, we are convinced that theINUSpheresis ® represents a promising treatment option for people with severe long-COVID, in the sense of an individual attempt at healing. Thisstudy and other interesting publications can be found belowlink . Study situation Long-COVID and therapeutic apharese Studies & publications Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions Symptoms of Long COVID Symptoms of long COVID vary from person to person but may include, but are not limited to:

Stoffwechselprozesse bilden die Grundlage aller lebenswichtigen Körperfunktionen. Diese Prozesse sind komplex und betreffen jeden Aspekt unseres Organismus. Im Inneren jeder Zelle des menschlichen Körpers finden ständig lebensnotwendige Stoffwechselprozesse statt. Wenn diese Abläufe aus dem Gleichgewicht geraten, sprechen wir von einer Stoffwechselstörung, die unbehandelt zu einer Stoffwechselerkrankung führen kann. METABOLIC DISEASES Homepage / Diseases/ Metabolic Diseases Metabolic processes form the basis of all vital body functions. These processes are complex and affect every aspect of our organism. Vital metabolic processes are constantly taking place inside every cell of the human body. If these processes become unbalanced, we speak of a metabolic disorder, which, if left untreated, can lead to a metabolic disease. The causes are varied and can be genetic or environmental. Metabolic Diseases Causes of metabolic diseases Metabolic diseases can have various causes. Here are some of the most common causes of metabolic diseases: Causes of metabolic diseases 01 Environmental factors Metabolic diseases can be influenced by various environmental factors. 02 Nutrition An unhealthy diet high in sugar, saturated fat and processed foods can increase the risk of metabolic diseases such as diabetes. 03 Environmental toxins Exposure to environmental toxins such as heavy metals, pesticides and air pollution can impair metabolism and increase the risk of metabolic diseases. 04 lifestyle An inactive lifestyle, smoking and excessive alcohol consumption can negatively affect metabolism and lead to health problems. 05 stress Chronic stress can affect hormonal balance and disrupt metabolism, which can increase the risk of metabolic diseases. 06 Genetic factors Congenital metabolic diseases are often due to genetic mutations. Some genetic defects are hereditary, while others occur spontaneously. Family predisposition plays an important role in the development of metabolic diseases. Examples of metabolic diseases causes FH is primarily caused by genetic changes in the genes for the LDL receptor (in about 80% of cases), apolipoprotein B-100 or the PCSK9 protein. These mutations impair the function of the LDL receptor and lead to impaired processing of LDL cholesterol in the body. Most affected people are heterozygous, meaning they have inherited an abnormal gene variant from one parent. They have a 20-fold increased risk of early cardiovascular disease and often develop symptoms of coronary heart disease before the age of 50. The homozygous form (inherited from both parents) is very rare and results in patients often dying of a heart attack before the age of 30 without appropriate treatment. The severity of the genetic mutation may influence cardiovascular risk differently in adulthood. Therefore, it is important to know patients' specific genetic defects to better guide their treatment. Treatment The main goal of treatment is to significantly reduce LDL cholesterol levels. Target values may vary depending on the stage of the disease. Typically, statins are preferred to lower cholesterol levels and a healthy lifestyle is recommended. In addition, new drugs such as PCSK9 inhibitors offer additional treatment options for people with FH. In more severe cases, lipoprotein apheresis may be required, which we will discuss in more detail below. Familial hypercholesterolemia (FH) is one of the most common inherited metabolic diseases that leads to elevated cholesterol levels in the blood. This in turn permanently increases the risk of cardiovascular diseases such as heart attacks and strokes. In Germany, an estimated 160,000 to 400,000 people are affected by the hereditary disease, which means that between 1:200 and 1:500 people have familial hypercholesterolemia. Unfortunately, FH is often not recognized in a timely manner and is not adequately treated. Probably only around 15% of cases in Germany have been diagnosed. Most people only find out about their FH if they already have heart problems or if there is a high incidence of heart attacks in their family. The disease is inherited, and people with FH usually have high cholesterol levels from birth that are difficult to control. There are different genotypes of FH that can influence the severity of the disease. It is important to diagnose and treat familial hypercholesterolemia early to minimize the risk of cardiovascular disease. Family members of those affected should also be tested for FH as the condition is inherited genetically and early diagnosis and treatment can be life-saving. Familial hypercholesterolemia INUSpheresis® INUSpherese® for familial hypercholersterolemia Lipoprotein apheresis is considered when there is a particularly severe lipid metabolism disorder that cannot be adequately treated even with lifestyle changes and the use of lipid-lowering medications. This is particularly the case if the patient already suffers from vascular disease or there is a risk that an existing vascular disease will progress or spread to other areas of the body. In rare cases where patients cannot tolerate lipid-lowering medications, lipoprotein apheresis may be a helpful option. The procedure itself has been known and used in conventional medicine for many years. In 2009, INUS Medical Center AG in Cham (Bavaria) developed INUSpheresis®, a special form of blood washing. In contrast to conventional filters used in lipoprotein apheresis, INUSpherese® uses filters with a finer pore size. This allows the removal of up to 80% of lipids from the blood plasma. Read more about how the INUSpherese® treatment works and how it works here. This method of treatment helps improve microcirculation while reducing inflammatory markers and fibrinogen levels. That's why we at ELLANN® use INUSpheresis® as an accompanying therapy for FH. In addition, we develop an individual concept for each patient for the long-term reduction of blood lipid levels and cardiovascular risk. Treatment INUSpheresis Details According to a report published in 2022study , lipoprotein apheresis (LA) has been described as the most effective treatment option currently available to achieve maximal lipid reduction in patients with familial hypercholesterolemia and lipoprotein(a) hyperlipidemia. Although lipoprotein apheresis (LA) is considered an invasive method, the side effects encountered are low and it shows the best results in preventing major cardiovascular events. It is believed that the significant reduction in cardiovascular complications in patients with significant lipid disorders achieved by LA is due not only to the dramatic reduction in lipid levels, but also to the removal of other pro-inflammatory and atherogenic factors. Atherogenic factors are risk factors that can promote the development of arteriosclerosis and cardiovascular diseases. You can find more interesting studies here. Study situation Studies & publications Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Das Chronic-Fatigue-Syndrom (CFS), auch als Chronisches Erschöpfungssyndrom bekannt, ist eine chronische Erkrankung mit einem vielseitigen Krankheitsbild. Die Hauptsymptome zeigen sich über einen langen Zeitraum (mehr als 6 Monate) als andauernde starke Erschöpfung, die durch Schlaf nicht zu beseitigen ist und sowohl körperlicher als auch geistiger und/oder seelischer Art sein kann. CHRONIC FATIGUE SYNDROME (CFS) Homepage / Diseases / Chronical Inflammation / Chronic Fatigue Syndrome (CFS) Chronic fatigue syndrome (CFS), also known as chronic fatigue syndrome, is a chronic disease with a diverse clinical picture. The main symptoms appear over a long period of time (more than 6 months) as persistent, severe exhaustion that cannot be eliminated by sleep and can be physical, mental and/or emotional. The care situation for patients with CFS in Germany has so far been very difficult because there are no specialized centers and many doctors have little knowledge of the disease and adequate therapeutic approaches. Chronic Fatigue Syndrome (CFS) Causes of CFS causes The exact mechanism of how chronic fatigue syndrome develops has so far only been partially understood. The disease begins with an infection - usually in full health. Possible triggers can be: Epstein-Barr virus (EBV) and other herpes viruses Dengue viruses Coxsackie viruses Influenza Borrelia Bacteria (Legionella, Coxial) There are a number of proven connections that suggest that CFS is an autoimmune disease in at least some patients. Most people with chronic fatigue syndrome are highly productive until the disease occurs. As a rule, the disorder occurs suddenly and often after a stressful event. These risk factors include: Immune defects More cases in the family Vulnerable phase with physical or psychological stress Symptoms The problem with CFS is that the symptoms that occur initially appear unspecific and are therefore not associated. They could also indicate other illnesses. What is striking, however, is that the symptoms of CFS appear suddenly. The main symptom is onesevere fatigue for at least six months, resulting in severe restriction of everyday activities. Other symptoms can include: ⎯⎯• Persistent signs of infection such as a sore throat, painful lymph nodes or a slightly elevated temperature ⎯⎯• Susceptibility to infections ⎯⎯• Joint pain ⎯⎯• Muscle pain ⎯⎯• Headache ⎯⎯• Sleep disorders despite severe fatigue ⎯⎯• Increase in infections ⎯⎯• newly occurring allergies ⎯⎯• Food intolerances ⎯⎯• Disorders of the autonomic nervous system, which include dizziness, rapid heartbeat and intestinal problems The symptoms are chronic in most patients and often lead to occupational disability. Those who are particularly seriously ill are dependent on care. Treatment of CFS Because the exact cause of CFS is unknown, there is no specific treatment. Treatment therefore focuses on relieving symptoms and improving quality of life. This may include the use of pain relief medications, cognitive behavioral therapy, and rest. INUSpheresis® INUSpherese® as a treatment option for CFS INUSpheresis® can help alleviate the symptoms of Chronic Fatigue Syndrome (CFS) by removing inflammatory substances from the body to reduce underlying inflammation. By eliminating these substances, patients have the opportunity to recover from the symptoms of CFS and improve their quality of life. We have compiled further information about INUSpheresis® for you here. Treatment INUSpheresis Details In onestudy from 2022, striking similarities between long COVID and chronic fatigue syndrome (CFS) were reported, suggesting viral and autoimmune causes. In both diseases, antibodies against certain neurotransmitter receptors play a crucial role. A similar increase in these autoantibodies was found in both patient groups examined. Washing blood with a special filter appears to be effective in reducing these antibodies and significantly improves the distressing symptoms of CFS patients. Therefore, this form of blood purification could be a promising therapeutic option for patients with long COVID and CFS, even if previously unknown antibodies and inflammatory mediators are involved. You can find more interesting studieshere. Study situation News & study situation Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Autoimmunerkrankungen resultieren aus einer fehlerhaften Funktion des körpereigenen Immunsystems, bei der es versehentlich körpereigene Zellen und Gewebe angreift, anstatt nur Krankheitserreger wie Bakterien und Viren zu bekämpfen. Es existieren zahlreiche verschiedene Arten von Autoimmunerkrankungen. AUTOIMMUNE DISEASES Homepage / Diseases / Autoimmune Diseases Autoimmune diseases result from improper functioning of the body's immune system, where it accidentally attacks the body's own cells and tissues instead of just fighting pathogens such as bacteria and viruses. There are many different types of autoimmune diseases. Autoimmune Diseases Causes of autoimmune diseases The exact causes of autoimmune diseases are not yet fully understood, but there are some factors that may play a role: Causes of autoimmune diseases 01 Genetic predisposition A genetic predisposition can increase the risk of autoimmune diseases. People with certain genes may be more susceptible to developing an autoimmune disease. These genes can influence the immune system and increase the likelihood of an incorrect reaction to the body's own tissues. 02 Environmental factors Various environmental factors such as infections, smoking, diet and exposure to pollutants can increase the risk of autoimmune diseases. Some infections can confuse the immune system by having similar structures or proteins to the body's own cells, which can cause the immune system to accidentally attack the body's own tissue. 03 Hormonal changes Hormonal changes, such as those that occur during pregnancy or menopause, can affect the immune system and increase the risk of autoimmune diseases. Sex hormones, particularly estrogen, may play a role in regulating the immune system. 04 Immune system imbalance A disturbed balance in the immune system, in which certain cells or proteins are overactive, can trigger or worsen autoimmune diseases. This can be triggered by a variety of factors, including genetic abnormalities. 05 stress Chronic stress can strain the immune system and lead to inflammation, which can promote autoimmune diseases. The mechanism by which stress influences autoimmune diseases is complex and still being researched. 06 Nutritional factors Recent studies suggest that certain dietary habits may influence the risk of autoimmune diseases. A balanced diet can help keep the immune system in a healthy balance. 07 Viral diseases Viral infections can play a role in the development of autoimmune diseases. This often happens through a mechanism called molecular mimicry. In molecular mimicry, certain proteins or structures on viruses or bacteria resemble those in the body's own tissue. The immune system can then fight the pathogens, but in some cases it can also attack its own tissues that contain similar proteins or structures. It is important to note that autoimmune diseases can vary widely and not all of these factors play a role in every case. The exact cause can vary from disease to disease. Examples of autoimmune diseases Rheumatoide Arthritis Hashimoto-Thyreoiditis Multiple Sklerose (MS) Polyneuropathie Rheumatoid arthritis Rheumatoid arthritis is an autoimmune disease in which the immune system attacks the joints. This leads to pain, inflammation and often joint deformation. Learn more Hashimoto's thyroiditis Hashimoto's thyroiditis is an autoimmune disease in which the immune system attacks the thyroid. This disrupts the thyroid's hormone production, leading to symptoms such as fatigue, weight gain and mood swings. Learn more Multiple sclerosis (MS) MS is an autoimmune disease of the central nervous system in which the immune system attacks the protective layer of nerve fibers known as myelin. This leads to a variety of neurological symptoms such as muscle spasms, vision problems and weakness. Learn more Polyneuropathy Polyneuropathy is a group of autoimmune diseases in which the immune system attacks the peripheral nerves. This can cause symptoms such as numbness, tingling, muscle weakness and pain in the extremities. Learn more Treatment of autoimmune diseases Anti-inflammatory drugs Anti-inflammatory medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) can be used in autoimmune diseases such as rheumatoid arthritis and lupus to reduce pain and inflammation. Corticosteroids are often prescribed to treat acute inflammatory attacks in various autoimmune diseases. Immunomodulating drugs Immunosuppressants such as methotrexate, azathioprine, and cyclosporine can suppress the immune system to reduce autoimmune reactions. Biological drugs such as TNF-alpha inhibitors are used to treat autoimmune diseases such as rheumatoid arthritis and Crohn's disease. Hormone therapy For autoimmune diseases that affect hormone production, such as Hashimoto's thyroiditis, hormone replacement therapy may be used to balance hormone levels in the body. Immunotherapy For some autoimmune diseases, immunotherapy may be considered to reprogram the immune system or modulate responses. Immunotherapy can be performed in a variety of ways, including the targeted removal of specific immune cells. The goal is to reduce harmful autoimmune reactions while maintaining the immune system's ability to fight pathogens. The choice of immunotherapy depends on the type of autoimmune disease, its severity and the individual needs of the patient. Physiotherapy and rehabilitation For autoimmune diseases that cause muscle weakness or joint problems, physical therapy and rehabilitation can help improve mobility and quality of life. Diet and lifestyle A balanced diet and a healthy lifestyle, including adequate exercise and stress management, can help relieve the symptoms of autoimmune diseases. surgery In some cases, surgery may be necessary to treat damage or complications from autoimmune diseases. For example, intestinal resection may be necessary for ulcerative colitis or Crohn's disease. Plasmapheresis In severe autoimmune diseases, especially if they are life-threatening, plasmapheresis can be considered as a last resort. Plasmapheresis, also known as therapeutic plasma exchange, involves the exchange of a large portion of the patient's plasma. The exchanged plasma is replaced either with a protein solution (human albumin) or the plasma from healthy donors. Examples of autoimmune diseases for which plasmapheresis may be considered include Guillain-Barré syndrome, myasthenia gravis, and certain forms of systemic vasculitis. Treatment options for autoimmune diseases depend on the specific disease and its severity. Some common approaches are listed below: INUSpheresis® INUSpherese® for autoimmune diseases TheINUSpheresis® is an advanced healing method for blood plasma purification, which aims to effectively separate harmful substances from the blood plasma. INUSpheresis® aims to filter out only disease-promoting (pathogenic) substances from the blood plasma, while healthy components of the plasma remain intact and are reintroduced to the body. This ensures that the organism continues to have all the nutrients and healthy components it needs. The plasma is not exchanged. INUSpherese® details In contrast to traditional blood washing, plasmapheresis or dialysis procedures, which remove a wide range of substances from the blood, INUSpheresis® aims to remove only pathogenic or harmful contaminants from the bloodstream. Targeted removal of harmful substances Preservation of vital components During treatment, vital elements such as electrolytes, proteins, nutrients, blood cells and antibodies in the patient's blood are not affected or removed. This helps maintain balance in the body. Specially developed filter INUSpheresis® uses specially designed filters that ensure only harmful or pathogenic substances are removed from the blood while the important components remain intact. Gentle and well-tolerated treatment Due to the targeted removal of harmful substances and the preservation of healthy components, INUSpheresis® is generally a gentle and well-tolerated treatment method. By removing harmful antibodies and other pathogenic factors from blood plasma, INUSpheresis® can help reduce inflammation, mitigate autoimmune reactions and relieve symptoms. However, the effect can be limited in time. In some cases, repeated INUSpherese® treatment may be necessary to keep the disease under control. INUSpheresis® appears to be a promising option for patients who require targeted removal of harmful substances from the bloodstream without affecting healthy blood components. However, as with all medical procedures, use should be carried out under medical supervision and tailored to the patient's individual needs. At ELLANN® The focus is on the safety and well-being of our patients. A special aspect that sets us apart from many other centers is the continuous presence ofMs. Kellermann , specialist in anesthesiology and intensive care medicine. Mode of action and benefits Galina Kellermann Specialist in anesthesia and intensive care medicine. ELLANN® team Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Die rheumatoide Arthritis ist eine Form von Arthritis, bei der das körpereigene Immunsystem die Gelenke angreift. Die Innenhaut der Gelenke (Synovialis) wird befallen, meist der Hände oder Füße. Die dadurch entstehenden Schwellungen und Schmerzen belasten Patienten sehr. RHEUMATOID ARTHRITIS (RA) Homepage / Diseases / Autoimmune Diseases / Rheumatoid Arthritis (RA) Rheumatoid arthritis is a form of arthritis in which the body's immune system attacks the joints. The inner skin of the joints (synovium) is affected, usually the hands or feet. The resulting swelling and pain are very stressful for patients. In many patients, certain antibodies are found in the blood, such as rheumatoid factor and anti-CCP antibodies (autoantibodies that are directed against components of the connective tissue). Today, the autoantibodies can be differentiated very well in the laboratory, so that early detection is possible. Rheumatoid arthritis affects approximately 1% of the population and is 2-3 times more common in women. It usually begins between the ages of 35 and 50, but can occur at any age. Children can also suffer from a form of rheumatoid arthritis (juvenile idiopathic arthritis). Rheumatoid Arthritis (RA) Causes of Rheumatoid Arthritis Causes of rheumatoid arthritis The exact causes of rheumatoid arthritis have not yet been fully clarified. However, it is assumed that different triggers are involved in the development. Genetic predisposition It is not yet known why the immune system attacks the joints. However, a genetic component is suspected, as familial clusters can be observed. Rheumatoid arthritis occurs three times more often in siblings and children of those affected than in people in whose families no one is affected by rheumatoid arthritis. Environmental influences There are other, largely unknown factors that can trigger or promote the onset of rheumatoid arthritis. Studies have shown above all that smoking increases the risk of the disease. In smokers, the disease is often more severe. Therapies are less effective for them. Other risk factors for rheumatoid arthritis include obesity and periodontal disease, as well as changes in the microbiome (the group of microorganisms that normally live in a specific part of the body, such as the digestive tract, mouth and lungs). Symptoms of rheumatoid arthritis In many cases, rheumatoid arthritis begins gradually, but can also manifest itself with sudden, severe symptoms. It is often the small finger and toe joints that initially show inflammation. In addition to the joints themselves, tendons, tendon attachments and ligaments can also be affected. Common symptoms of RA: ⎯⎯• Painful, warm, red and swollen joints (inflammation) ⎯⎯• Stiffness in the affected joints about 1 hour after getting up ⎯⎯• General feeling of illness with: Mild fever Tiredness and exhaustion Loss of appetite and weight loss Deterioration over time can result in the following: ⎯⎯• Inability to fully flex or extend affected joints ⎯⎯• Permanently deformed joints, especially in the hands and fingers Rheumatoid arthritis can cause problems in other organs in addition to the joints. These so-called comorbidities can e.g. B. affect the heart and vessels or the lungs. Sexual dysfunctions Treatment options for rheumatoid arthritis There are several treatment options that can help relieve the symptoms of RA and slow the progression of the disease. Here are some of the most common treatment options for rheumatoid arthritis: Drug therapies Conventional drug therapy for rheumatoid arthritis includes the use of anti-inflammatory medications, corticosteroids, and basic medications such as methotrexate. In recent years, bioengineered protein substances called biologics have also been used to suppress inflammation in the body, relieve symptoms and slow disease progression. Physiotherapy and rehabilitation Physical therapy can help improve joint mobility, strengthen muscles, and relieve pain. A physical therapist can recommend customized exercises and techniques to control symptoms and improve quality of life. Occupational therapy Occupational therapy focuses on helping patients cope better in everyday life. An occupational therapist can help use adaptive equipment to facilitate activities of daily living, as well as provide pain relief and joint protection techniques. Nutrition A healthy diet can have a positive impact on rheumatoid arthritis symptoms. It is recommended to eat a balanced diet rich in fruits, vegetables, whole grains and omega-3 fatty acids. Some studies have shown that certain supplements, such as fish oil, may also have anti-inflammatory properties. Stress management Stress can worsen rheumatoid arthritis symptoms. It is therefore important to reduce stress and integrate relaxation techniques such as meditation, yoga or breathing exercises into everyday life. INUSpheresis® INUSpherese® as an accompanying therapy option for MS An alternative treatment option for rheumatoid arthritis is INUSpherese®, an innovative method of detoxifying the body that is used for rheumatoid arthritis and other chronic diseases. This therapy is based on a blood plasma purification technique in which harmful substances such as toxins, inflammatory mediators and pathogenic antibodies are removed from the blood. The purified blood plasma is then returned to the body. This therapy can help relieve rheumatoid arthritis symptoms and improve patients' quality of life. INUSpheresis® should only be carried out by qualified specialists. In Germany there are specialized centers and partner practices that have the necessary equipment and specialist knowledge. As a certified INUS partner, ELLANN® is one of the few centers that specializes in INUSpheresis® and accompanying therapies for the treatment of chronic inflammatory diseases, environmental diseases, autoimmune diseases and long COVID. It is important to work with a specialist to find the most appropriate treatment options. Each case of rheumatoid arthritis is unique and requires an individual treatment strategy. doctors INUSpheresis Details Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Entzündungen sind natürliche Abwehrreaktionen des Körpers, die normalerweise kurzzeitig auftreten, um Krankheitserreger zu bekämpfen. Allerdings können sie zu Krankheiten führen, wenn sie chronisch werden. CHRONIC INFLAMMATION Homepage / Diseases / Chronical Inflammation Inflammation is the body's natural defense reaction, which usually occurs briefly to fight pathogens. However, they can lead to illness if they become chronic. In cases of chronic inflammation, the body is unable to effectively defend itself against the constant release of inflammatory substances into organs and tissues. This results in inflammatory markers in the blood being permanently elevated and diseased cells in the inflamed area being gradually replaced by connective tissue. The inflamed tissue is broken down and slowly heals by forming scars. Chronic inflammation, depending on its location in the body, can permanently impair the normal function of affected tissues, even if treatment is provided. Chronical Inflammation Causes of chronic inflammation Chronic inflammation is now widespread and affects millions of people in developed countries and can be triggered by various causes. Here are some common causes of chronic inflammation: Causes of chronic inflammation 01 Infections Long-term infections, such as bacterial, viral or parasitic infections, can cause chronic inflammation. 02 Autoimmune diseases Autoimmune diseases such as rheumatoid arthritis, lupus, and Crohn's disease cause the immune system to attack healthy tissue, which can lead to chronic inflammation. 03 Nutrition An unbalanced diet high in saturated fats, refined sugars, and processed foods can promote inflammation. 04 Overweight Overweight and obesity (obesity) are associated with chronic inflammation because fatty tissue can produce inflammatory substances. 05 stress Chronic stress can affect the immune system and contribute to inflammation. 06 genetics Some people are at higher risk of chronic inflammation due to their genetic makeup. 07 Environmental factors Environmental toxins, air pollution and certain chemicals can promote chronic inflammation. Environmental factors as triggers Chronic inflammation has been increasing worldwide for decades, and the causes are diverse. Environmental toxins, which are ubiquitous, especially in industrialized countries, play an important role. New chemicals that are not beneficial to human health have found their way into our daily lifestyle. They can be found in household cleaning products, personal care products, cosmetics, textiles, indoor pollution, air pollution and, above all, in food. Depending on the individual's ability to detoxify, these chemicals accumulate in different tissues and organs. This can lead to numerous health problems, including eye disease, heart problems, kidney and thyroid disease, and neurological disorders. Clinical pictures and effects Primär-chronische Entzündungen Sekundär-chronische Entzündungen Primary chronic inflammation develop gradually and manifest themselves through slow or intermittent symptoms. The duration of an inflammatory attack often lasts longer than four weeks and complete healing is usually not possible. Examples of primary chronic inflammation are diseases such as type 1 diabetes Autoimmune diseases HowRheumatoid arthritis ,multiple sclerosis orCrohn's disease , in which symptoms gradually progress. Learn more Secondary chronic inflammationusually occur after an acute inflammation that has not completely healed. The healing process is often lengthy. Examples of such chronic forms are diseases such as chronic hepatitis, chronic myocarditis, stomach ulcer (ulcer) or chronic tonsillitis. These often occur after untreated acute inflammation and manifest as long-lasting problems. Learn more A variety of diseases can be caused by chronic inflammation. We differentiate between primary-chronic inflammation and secondary-chronic inflammation: Symptoms of chronic inflammation Chronic inflammation often begins gradually and symptoms often worsen over time. Chronic inflammation can cause a variety of symptoms that vary depending on the organ or tissue affected. Here are some common symptoms of chronic inflammation: Pains Chronic inflammation is often accompanied by persistent pain that may occur near the affected area. swelling Inflammation often leads to swelling and can cause tissue damage. Redness Inflamed areas may be red and warmer than the surrounding skin. Stiffness Joints can become stiff and less mobile when affected by inflammation. exhaustion Chronic inflammation can cause general tiredness and fatigue. Fever An increased body temperature can indicate inflammation, although this is not always the case. weight loss For some people, chronic inflammation can lead to unwanted weight loss. Organ change Depending on the area affected, chronic inflammation can lead to permanent organ damage. anamnese The detailed medical history survey serves to collect information about symptoms, previous history and possible risk factors. Physical examination A thorough physical examination may reveal evidence of inflammation, such as swelling, redness, pain, or limited mobility. Laboratory tests In laboratory tests, doctors use special blood tests to determine whether there is inflammation in the body. Various markers are examined here: C-reactive protein (CRP): This is where the biomarker CRP is determined in the blood, which is often used to assess inflammation in the body. Erythrocyte sedimentation rate (ESR): The ESR measures how quickly red blood cells settle in the blood. This value is often used to detect inflammation or other diseases in the body. Interleukins 1, 6 and 8: The values provide information about the presence of inflammatory messengers called interleukins, which are crucial in the body's immune response to infections and inflammation. Tumor necrosis factor alpha (TNF-α): This test examines TNF-α in the blood, a protein that is involved in inflammatory processes. Imaging procedures Depending on whether a particular inflammation is suspected, an imaging test such as X-rays, CT scans or MRI scans may be required to examine the affected areas in more detail. biopsy In some cases, a tissue biopsy may be necessary to make an accurate diagnosis. This involves taking a small sample of tissue and examining it under a microscope. Endoscopy If there is inflammation in the digestive tract, an endoscopy can be performed to more accurately assess the condition of the mucous membrane. Diagnostics for chronic diseases Chronic inflammatory diseases often affect more than just one organ system. The diagnosis of chronic inflammation can be complex and depends on the type of inflammation and the patient's individual circumstances. At ELLANN® we work together with specialized doctors on an interdisciplinary basis, because thorough diagnostics are essential for optimal therapy planning. Below are some common diagnostic procedures for chronic inflammation: Treatment of chronic inflammation The treatment of chronic inflammatory diseases can vary depending on the type of disease and individual health status. Here are some general approaches to treating such conditions: Medication Anti-inflammatory medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to relieve pain and inflammation. For autoimmune diseases, immunosuppressants or biologics may be prescribed to suppress the immune system and reduce inflammation. Corticosteroids can be used in acute bursts to quickly combat inflammation. Lifestyle changes A healthy diet can help reduce inflammation. Antioxidant-rich foods such as fruits and vegetables are recommended. Regular exercise can improve joint function and relieve pain. Stress management techniques such as yoga or meditation can also be helpful. physical therapy Physical therapy can help improve mobility and reduce pain in affected areas. Surgical interventions In some cases, surgery may be necessary to remove damaged tissue or repair joints.In some cases, surgery may be necessary to remove damaged tissue or repair joints. Alternative therapies Some people seek alternative approaches such as acupuncture or homeopathy to relieve their symptoms. Cause therapy with INUSpherese® for chronic inflammatory diseases With INUSpheresis®, we filter the blood to specifically remove substances that promote disease and cause inflammation, such as environmental toxins and misdirected autoimmune antibodies. At the same time, we demonstrably reduce the amount of inflammatory messengers such as CRP or TNF-a in the blood with every INUSpheresis®. With the help of INUSpherese® therapy, we address the causes and can thus have a positive influence on chronic inflammation. At ELLANN® we do not rely on medications that often have side effects to alleviate symptoms, but rather concentrate on specifically removing the disease-promoting factors from the body. Treatment INUSpheresis Details INUSpheresis® The method of therapeutic apharesis has been mentioned in over 21,000 scientific studies (PubMed, January 2021). The therapy concept of INUSpheresis® is also described in numerous publications. We have put together a selection of current articles and scientific studies for you: Effectiveness and study situation News & study situation Alzheimer's dementia syndrome is a progressive brain disease that affects memory, thinking and behavior. Abnormal protein deposits in the brain are characteristic of this disease. Alzheimer dementia syndrome learn more Lyme disease (Lyme disease) Lyme disease is a tick-borne infectious disease caused by the bacterium Borrelia burgdorferi. It can cause a variety of symptoms, including skin rash, joint pain and neurological problems. learn more Chronic Fatigue Syndrome (CFS) Chronic fatigue syndrome is a condition that causes persistent and extreme fatigue that is not relieved by rest or sleep. It may be accompanied by other symptoms such as muscle pain, headaches and problems concentrating. learn more Chronic hepatitis C Chronic hepatitis C is a liver disease caused by the hepatitis C virus. It can take years or even decades for symptoms to appear. When they occur, they can cause liver problems such as inflammation and scarring, which can lead to cirrhosis and liver cancer. coming soon Ulcerative colitis Ulcerative colitis is a chronic inflammatory disease of the intestine in which the natural defense mechanisms of the intestine are compromised. Immune system is disturbed. This can lead to inflammation and ulceration of the colon and manifest itself in symptoms such as diarrhea, abdominal pain and weight loss. learn more Crohn's disease Crohn's disease is another chronic inflammatory bowel disease in which there is a barrier disorder in the intestine, which contributes to the immune system's reaction and thus inflammation. This can lead to severe abdominal pain, diarrhea, weight loss, and inflammation in various parts of the digestive tract. learn more Find out more about how it works and the treatment process at INUSpherese®. Therapy indications The positive benefits of INUSpheresis® have already been proven in numerous clinical pictures. We at ELLANN® treat as part of our holistic therapy approachAutoimmune diseases ,Environmental diseases ,Metabolic diseases including the following chronic inflammatory diseases: Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Die Gründung von ELLANN® durch ELLER & KELLERMANN erfolgte mit dem klaren Fokus auf Entgiftungsbehandlungen. Beide Institutionen vereinen sich, um ein einzigartiges Therapiekonzept zu realisieren, das auf vier grundlegenden Pfeilern basiert:  ELLANN® part of ELLER & KELLERMAN TREATMENTS Homepage / Treatments The founding of ELLANN® by ELLER & KELLERMANN was carried out with a clear focus on detoxification treatments. Both institutions come together to implement a unique therapy concept based on four fundamental pillars: DETOXIFICATION NUTRITION MOVEMENT RECREATION INUSpheresis® NAD+ and other infusion therapies Heamo laser® Environmental medicine advice Therapy offer acupuncture Laser therapy IHHT IHHT under stress TCM medicine Osteopathy Personal training Pain therapy Nutritional medicine according to EPD Access to the entire range of therapies ELLER & KELLERMAN , such as.: Diagnosis A careful diagnosis at the beginning of every treatment is like a guide for our doctors and therapists. It makes it possible to identify the causes of the symptoms and, based on this, to design an individually tailored treatment strategy. An accurate diagnosis is essential as it lays the foundation for effective therapy aimed at providing you with the best possible help and promoting your well-being. Excerpt from the ELLANN® diagnostics offering: ⎯⎯• Laboratory analysis ⎯⎯• Eluate analyses ⎯⎯• ECG ⎯⎯• Darkfield diagnostics Access to ELLER KELLERMANN's extensive range of diagnostics, such as: ⎯⎯• Microbiome analysis ⎯⎯• Ultrasound examination ⎯⎯• X-ray diagnostics ⎯⎯• MRI diagnostics ⎯⎯• VNS analysis (vegetative nervous system) ⎯⎯• Bioimpedance analysis ⎯⎯• Spectrophotometry Our dedicated and knowledgeable medical team is dedicated to supporting your health and helping you on your road to recovery TEAM Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions Our focus at ELLANN® is on holistic detoxification and evidence-based complementary medicine. The INUSpheresis® we use is a treatment method that helps the body eliminate harmful proteins (such as malformed antibodies), metabolic products (such as cholesterol) and toxic substances (such as heavy metals and microplastics). Our goal is to bring the disturbed metabolism, the inflammatory processes and the immune system back into natural balance. We use INUSpherese® in various areas of application, including:Environmental pollution ,Lipid diseases ,chronic inflammation as well as afterInfectious diseases and atAutoimmune diseases . Discover our unique treatment concept for holistic health. From diagnosis and treatment to aftercare and prevention – with us you are in the best hands. Lipid diseases Environmental Pollution Autoimmune Diseases Chronical Inflammation

Der Begriff "Umwelterkrankungen" bezieht sich auf Krankheiten, die nachweislich durch spezifische Umweltfaktoren begünstigt, ausgelöst oder aufrechterhalten werden. Viele Erkrankungen werden in Verbindung mit Umweltfaktoren gebracht. Einige können auch ohne diese Einflüsse auftreten (z. B. Migräne), während andere ausschließlich durch externe Faktoren entstehen (z. B. Pollenallergien).  ENVIRONMENTAL DISEASES Homepage / Diseases / Environmental Diseases The term “environmental diseases” refers to diseases that have been shown to be promoted, triggered or maintained by specific environmental factors. Many diseases are associated with environmental factors. Some can occur without these influences (e.g. migraines), while others arise solely from external factors (e.g. pollen allergies). Our daily lives bring us into contact with a variety of toxic substances. Pesticides are contained in many agricultural products, and foods contain numerous additives such as flavors, colors and preservatives. Cosmetics and care products can also contain toxic ingredients. We even find chemicals in the air we breathe, such as solvents from paint and other furnishings. A person's ability to detoxify depends heavily on their genetic factors. Some people are better at breaking down toxins than others, based on genetic variations in enzymes involved in detoxification. These genetic differences may cause some people to be more sensitive to environmental toxins and have a higher risk of health problems. Environmental Diseases Causes of environmental diseases Environmental diseases are, as the name suggests, caused by various environmental factors. These factors can be roughly divided into biological, chemical and physical influences. These “trigger effects” can trigger one or more environmental diseases. Biological environmental factors Biological environmental factors include pathogens that can colonize under certain conditions, as well as allergens such as pollen and ticks. Mold and pathogenic germs can spread under unfavorable environmental conditions. Another aspect is introduced poisonous plants from tropical regions. Chemical environmental factors Chemical environmental factors include environmental toxins such as arsenic, lead, chromium, pesticides, mercury and radioactive particles. In addition, synthetic compounds enter the environment through products such as cosmetics, medicines and detergents and accumulate there. Air pollutants such as nitrogen oxides and particulate matter, as well as construction-related pollutants such as asbestos and polychlorinated biphenyls, also contribute to environmental diseases. Physical environmental factors Physical environmental factors include radioactive radiation, infrasound, noise, UV radiation and electromagnetic fields. These factors can also cause health problems. Examples of environmental diseases MCS (Multiple Chemical Sensitivity) Toxikologisch induzierter Toleranzverlust (TILT) Multiple chemical sensitivity (MCS) is a medical term for increased sensitivity to various chemical substances that would not normally cause health problems at low concentrations. This sensitivity leads to symptoms that can manifest in various organ and systemic systems of the body. It is important to know that these symptoms occur when levels of these chemical substances are well below levels considered harmful to most people. In addition, in people with MCS, the body's ability to detoxify is impaired. In the past, MCS has often been associated with psychosomatic elements. This may be because neuropsychological symptoms are often prominent and because women are more commonly affected by MCS (for various reasons). Unfortunately, this has led to some stigmatization of women suffering from MCS, and their complaints have often not been taken seriously. Environmental diseases are now being intensively discussed and researched worldwide and those affected are taken seriously in their suffering. Learn more Toxicologically induced loss of tolerance (TILT) is a two-stage disease process. It affects a specific group of people who are prone to a variety of symptoms and new intolerances after a large amount of chemical substances or repeated minor exposures. Symptoms of TILT may include: fatigue Headache weakness skin rash Mood swings Memory problems Difficulty concentrating (often referred to as "brain fog" or brain fog) Breathing problems Unlike known disease mechanisms such as cancer or hormonal imbalances, which develop gradually, the explanation for TILT does not fit into standard toxicology or allergy research. TILT takes place in two phases: Initiation (Phase I) This phase begins when a person is exposed to certain chemicals that normally affect the immune system and/or nervous system. In this phase, the chemical must interact with one or both of these systems in a way that makes the person sensitive to future triggers. Triggering (Phase II) After initiation, affected individuals are no longer able to tolerate everyday exposures to various chemical substances, even those that they previously tolerated well. These can be various things such as fragrances, cleaning products, smoke, certain foods or medications, and even materials that come into contact with the skin. Exposure to these triggers results in the symptoms mentioned above. Even foods and medications that were previously tolerated can now trigger symptoms. Overall, TILT causes the body to become hypersensitive to many different substances, which can lead to a variety of health problems. Learn more There are also other illnesses that can occur as environmental illnesses, including: ADHD Allergies asthma Autoimmune diseases high blood pressure Chronic fatigue syndrome (CFS) intestinal inflammation depressions Fibromyalgia migraine multiple sclerosis Neurodermatitis Polyneuropathies However, this is just a list of common environmental diseases, as there are many others that are linked to environmental factors. Symptoms Environmental toxins can cause different symptoms and health consequences, depending on the type of toxin and the exposure time (how long one was exposed to the toxin). Here are some common symptoms: Respiratory problems Some environmental toxins, such as air pollutants and smoke, can cause respiratory problems such as coughing, shortness of breath and asthma. Skin problems Exposure to certain chemicals or pollutants may cause skin irritation, rashes or dermatitis. Gastrointestinal complaints Ingesting contaminated water or food can cause gastrointestinal symptoms such as nausea, vomiting and diarrhea. Headache and dizziness Some toxins can cause neurological symptoms such as headaches, dizziness and confusion. Reproductive problems Some environmental toxins can affect fertility and cause reproductive problems. Allergic reaction Some people may develop allergic reactions to certain environmental toxins. Long-term exposure to environmental toxins can cause significant health problems, including Cancer, organ failure andserious neurological disorders . Other long-term consequences can include: depression miscarriage sleep disorders Metabolic diseases (leaky gut syndrome) It is important to note that the symptoms and consequences of environmental toxins can vary depending on individual sensitivity as well as ability to detoxify, length of exposure, and type of toxin. Long-term health consequences Treatment of environmental diseases The treatment of environmental diseases is very individual as the triggers and symptoms can vary from person to person. Some approaches are listed below: Avoiding triggers The first step in managing environmental illnesses is to identify triggers and minimize exposure to them. This may mean removing or avoiding certain foods, chemicals, fragrances, or other substances from the immediate environment. Environmental control Improving air quality in your home and work environment can help reduce symptoms. This may include removing sources of pollution, using air purifiers, and improving ventilation. Nutrition A well-thought-out diet can help control symptoms. A nutritionist can help you create a diet tailored to your specific intolerances. Supportive therapy Some patients benefit from supportive therapy approaches aimed at relieving symptoms. This includes the use of pain relievers, antihistamines, or other medications that may be prescribed depending on individual needs. Psychological support Since environmental illnesses are often associated with psychological stress, support from a psychologist or psychiatrist can be helpful in dealing with the emotional challenges of the illness. detoxification INUSpherese® therapy is an advanced method for purifying blood plasma, also known as environmental apheresis. By using intelligent filter systems, INUSpherese® offers an individually adapted detoxification method that is also gentle on the patients. INUSpheresis® INUSpherese® for environmental diseases INUSpheresis® aims to strengthen the immune system and support the body's own self-healing powers. This is done by clearing the blood plasma of harmful substances, such as pathogens and environmental toxins, which normally stress the immune system and can severely impact overall health. The use of INUSpheresis® is particularly relevant for people who suffer from chronic inflammation, autoimmune diseases or environmental stress. This therapy can help to significantly improve the quality of life of these patients. It is advisable to work with a specialized medical professional who will help develop a tailored treatment strategy and find the optimal solution for the individual situation. As a certified INUSpheresis® center, ELLANN® specializes in the treatment of environmental diseases and offers you professional support from diagnosis to therapy and subsequent prevention. Find out more about this under Treatment or arrange a personal consultation. Treatment Personal appointment The method of therapeutic apharesis has been mentioned in over 21,000 scientific studies (PubMed, January 2021). Also the therapy concept The German Environmental Study on Health, also abbreviated as GerES, is a comprehensive study of the pollution levels of the population in Germany. This study has been carried out at regular intervals by the Federal Environment Agency since 1985. GerES VI (2023–2024): Research teams are currently collecting current data on the environmental impact of the adult population across Germany on behalf of the UBA. The teams visit the participants at home and collect urine and blood samples, conduct interviews and take samples of, among other things, drinking water, house dust and indoor air. For more information, see the followinglink . INUSpherese® is described in numerous publications. We have put together a selection of current articles and scientific studies for you: German environmental study News & study situation Study situation The effects of environmental toxins on health are being intensively discussed and researched by scientists around the world. There are numerous publications that...Google Scholar orPubmed can be found. We regularly provide you with particularly interesting information under Studies and News. Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

Die Colitis ulcerosa ist eine chronische Entzündung der Schleimhaut des Dickdarms. Sie verläuft in Schüben, so dass sich Krankheitsphasen mit symptomfreien Zeiten abwechseln. Die Colitis ulcerosa betrifft nur den Dickdarm und bleibt auf die oberste Schicht der Darmwand beschränkt, nämlich die Darmschleimhaut. Dort bilden sich „Geschwüre“, also Wunden und flache Defekte in der Schleimhaut. Die Erkrankung verläuft in Schüben und ist durch verschiedene Symptome gekennzeichnet. ULCEROSAL COLITIS Homepage / Diseases / Chronical Inflammation / Ucelerotic Colitis Ulcerative colitis is a chronic inflammation of the lining of the colon. It progresses in spurts, so that phases of illness alternate with periods without symptoms. Ulcerative colitis only affects the large intestine and is limited to the top layer of the intestinal wall, namely the intestinal mucosa. “Ulcers” form there, i.e. wounds and shallow defects in the mucous membrane. The disease progresses in episodes and is characterized by various symptoms. The long-term risk of colorectal cancer is increased compared to people who do not suffer from ulcerative colitis. Ulcerative Colitis Causes of Ulcerative Colitis Causes of Ulcerative Colitis The exact causes of ulcerative colitis are not yet fully known. However, it is assumed that a combination of genetic predisposition, environmental influences and a disturbed intestinal barrier can promote the development of the disease. Genetic predisposition There is a genetic predisposition to ulcerative colitis. If other family members have inflammatory bowel disease, the risk of the disease is increased. However, only the predisposition is inherited, not the disease itself. Environmental influences Certain environmental influences can promote the occurrence of ulcerative colitis. These include infections, certain food components or lifestyle. It is thought that improved hygiene standards and a Western lifestyle may increase the risk of the disease. Impaired intestinal barrier In people with ulcerative colitis, the protective mucous layer on the intestinal lining is often thinner than in healthy people. This weakens the intestinal barrier and allows bacteria and other harmful substances to penetrate the intestinal wall more easily. This leads to activation of the immune system and an inflammatory response. Symptoms of Ulcerative Colitis Ulcerative colitis can cause a variety of symptoms that may occur during an acute flare-up. The disease often progresses in episodes, with phases alternating with and without symptoms. The typical symptoms of ulcerative colitis include: Other symptoms can include: ⎯⎯• Diarrhea, often mixed with blood or mucus ⎯⎯• Crampy abdominal pain, often in the left lower abdomen ⎯⎯• Bleeding from the anus and anemia as a result of the bleeding ⎯⎯• Fever and general feeling of illness ⎯⎯• Weight loss ⎯⎯• Fatigue ⎯⎯• Constant urge to defecate with the feeling of having to defecate urgently or uncontrollably ⎯⎯• Frequent bowel movements, up to 20 times per day ⎯⎯• Nocturnal bowel movements Complaints outside the intestines are often expressed through inflammation: ⎯⎯• Skin ⎯⎯• Eyes ⎯⎯• Joints Symptoms can vary depending on the extent and severity of the inflammation. It is important to note that not all patients with ulcerative colitis have all symptoms and that symptoms can also vary from person to person. Treatment options for Ulcerative Colitis Treatment for ulcerative colitis aims to control inflammation and relieve symptoms. The therapy usually takes place in close collaboration with a specialist in gastroenterology and can consist of various measures. Here are some therapy options: Medication There are several anti-inflammatory medications that can be used to treat ulcerative colitis. These include aminosalicylates, corticosteroids, immunosuppressants and biologics. The choice of medication depends on the severity of the disease and the individual needs of the patient. Nutritional therapy A healthy and balanced diet plays an important role in the treatment of ulcerative colitis. In some cases, a special diet, such as the anti-inflammatory diet, may be helpful to relieve symptoms and support gut health. Surgical interventions In severe cases or complications, surgery may be necessary. The affected section of intestine can be removed to relieve symptoms and improve the patient's quality of life. However, surgery is usually only necessary if other treatment methods do not provide sufficient relief. It is important to note that treatment of ulcerative colitis must be individualized and that regular care from a gastroenterologist is important to monitor the progression of the disease and adjust therapy accordingly. INUSpheresis® INUSpherese® for ulcerative colitis The INUSpherese® treatment aims to address the underlying causes and thus have a positive influence on chronic inflammation. With INUSpherese® technology, we use blood filtration to specifically eliminate harmful substances that contribute to disease promotion and inflammation, such as environmental toxins and misdirected autoimmune antibodies. At the same time, a demonstrable reduction in inflammatory messengers such as CRP or TNF-a in the blood can be achieved. The aim of INUSpheresis® is to improve the patient's well-being and health in the long term. It can help strengthen the immune system and the body's own self-healing powers. However, it is important to emphasize that INUSpheresis® is a medical procedure and should only be performed by qualified professionals. There are only a few centers in Germany that offer this technology and it is mostly used by experienced doctors in combination with other holistic therapeutic approaches. As one of the few practices in Germany, we at ELLANN® work with the innovative therapy INUSpherese®. As a certified INUS partner, our aim is to help our patients free their bodies from toxic burdens and improve their health in the long term. Treatment INUSpheresis Details Various studies have already been carried out on the effectiveness of INUSpherese®. These show promising results in the treatment of various diseases such asulcerative colitis, rheumatoid arthritis ,Polyneuropathy ,Crohn's disease . We have put together some interesting studies for you here. Study situation News & study situation Which diagnoses can INUSpheresis® help with? ⎯⎯• Allergies ⎯⎯• Lyme disease ⎯⎯• Chronic fatigue syndrome (CFS) ⎯⎯• Chronic hepatitis C ⎯⎯• Hashimoto ⎯⎯• Hyperlipidemia ⎯⎯• Crohn's disease ⎯⎯• multiple sclerosis ⎯⎯• Multiple Chemical Hyper- sensitivity syndrome (MCS) ⎯⎯• Parkinson's ⎯⎯• Post-COVID syndrome ⎯⎯• Post-vac syndrome ⎯⎯• Rheumatism (chronic inflammatory) ⎯⎯• Heavy metal poisoning ⎯⎯• and more What exactly is filtered by INUSpherese®? INUSpheresis® was developed to remove a variety of disease-promoting substances and toxic substances from the blood. These include environmental toxins, heavy metals, allergens, metabolic products, inflammatory messengers, infection toxins and harmful proteins. Specially developed filters make it possible to specifically filter out these pollutants while preserving healthy components of the blood. INUSpherese® does not affect your vaccination protection because antibodies and immune cells that are responsible for your vaccination protection are preserved. This makes INUSpheresis® an extremely effective method for cleaning blood plasma and supporting general well-being and health. Ist die INUSpheresis® a blood wash? INUSpheresis® is not a conventional blood wash or plasma exchange method. It is also not dialysis, in which urinary substances are filtered out. INUSpheresis® is characterized by the targeted removal of harmful substances, while essential and healthy components of your blood remain untouched. This includes vital electrolytes, proteins, nutrients, blood cells and antibodies. The use of specially developed filters ensures that only pathogenic contamination is removed during the treatment. This makes the treatment particularly gentle and generally very well tolerated. How many INUSpherese® treatments are necessary? The number of INUSpherese® treatments required depends on your individual health status and health goals. A basic cycle of two treatments within 48 hours is recommended. For more intensive needs, such as extensive heavy metal elimination or complex clinical pictures, a third and even fourth treatment session every 6 to 7 weeks can make sense. Your personal treatment plan will be drawn up by our doctors after a detailed consultation. How much does an INUSpherese® treatment cost? An INUSpherese® therapy, which consists of two treatments, accompanying infusion concepts and a preparatory medical consultation, is usually priced between €5,400 and €5,700. This cost information is intended to serve as a rough guide, as the exact investment can vary depending on your individual health condition and any additional therapy options. As part of the therapy planning, you will receive detailed advice and a detailed cost overview that is individually tailored to your health goals. Frequently asked Questions

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